Literature DB >> 10225417

The diversity of the lipoxygenase family. Many sequence data but little information on biological significance.

H Kuhn1, B J Thiele.   

Abstract

Lipoxygenases form a family of lipid peroxidising enzymes, which oxygenate free and esterified polyenoic fatty acids to the corresponding hydroperoxy derivatives. They are widely distributed in both the plant and animal kingdoms. During the last couple of years more and more lipoxygenase isoforms have been discovered but for most of them the biological significance remains unclear. This review attempts to classify the currently known mammalian lipoxygenase isoforms and critically reviews the concepts for their biological importance.

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Year:  1999        PMID： 10225417     DOI： 10.1016/s0014-5793(99)00396-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  68 in total

1.  12-Lipoxygenase overexpression in rodent NG108-15 cells enhances membrane excitability by inhibiting M-type K+ channels.

Authors:  Y Takahashi; H Kawajiri; T Yoshimoto; N Hoshi; H Higashida
Journal:  J Physiol       Date:  1999-12-15       Impact factor: 5.182

2.  Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements.

Authors:  O Dransfeld; I Rakatzi; S Sasson; A Gruzman; M Schmitt; D Häussinger; J Eckel
Journal:  Biochem J       Date:  2001-10-01       Impact factor: 3.857

3.  Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population.

Authors:  Kai Zhang; Yuan-yuan Wang; Qi-ji Liu; Hui Wang; Fang-fang Liu; Zhi-yong Ma; Yao-qin Gong; Li Li
Journal:  Heart Vessels       Date:  2010-07-31       Impact factor: 2.037

Review 4.  Functional and pathological roles of the 12- and 15-lipoxygenases.

Authors:  Anca D Dobrian; David C Lieb; Banumathi K Cole; David A Taylor-Fishwick; Swarup K Chakrabarti; Jerry L Nadler
Journal:  Prog Lipid Res       Date:  2010-10-21       Impact factor: 16.195

Review 5.  Location, location, location: compartmentalization of early events in leukotriene biosynthesis.

Authors:  Marcia E Newcomer; Nathaniel C Gilbert
Journal:  J Biol Chem       Date:  2010-05-27       Impact factor: 5.157

6.  Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.

Authors:  Shunxing Rong; Qiang Cao; Mingxia Liu; Jeongmin Seo; Lin Jia; Elena Boudyguina; Abraham K Gebre; Perry L Colvin; Thomas L Smith; Robert C Murphy; Nilamadhab Mishra; John S Parks
Journal:  J Lipid Res       Date:  2012-01-25       Impact factor: 5.922

Review 7.  Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species.

Authors:  Kyung-Jin Cho; Ji-Min Seo; Jae-Hong Kim
Journal:  Mol Cells       Date:  2011-03-18       Impact factor: 5.034

8.  A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation.

Authors:  Gianguido Coffa; Alan R Brash
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-20       Impact factor: 11.205

9.  Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice.

Authors:  Peter B Anning; Barbara Coles; Alexandra Bermudez-Fajardo; Patricia E M Martin; Bruce S Levison; Stanley L Hazen; Colin D Funk; Hartmut Kühn; Valerie B O'Donnell
Journal:  Am J Pathol       Date:  2005-03       Impact factor: 4.307

10.  Regiospecific enzymatic oxygenation of cis-vaccenic acid during aerobic senescence of the halophilic purple sulfur bacterium Thiohalocapsa halophila.

Authors:  Daphné Marchand; Vincent Grossi; Agnès Hirschler-Rea; Jean-François Rontani
Journal:  Lipids       Date:  2002-06       Impact factor: 1.880
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