Literature DB >> 10220210

Potential impact of a change in the diagnostic criteria for diabetes mellitus on the prevalence of abnormal glucose tolerance in a local community at risk of diabetes: impact of new diagnostic criteria for diabetes mellitus.

M J Davies1, S Muehlbayer, P Garrick, P G McNally.   

Abstract

AIMS: To compare the prevalence of diabetes and abnormal glucose metabolism using conventional and suggested new WHO and new ADA criteria in a group of people with symptoms of diabetes.
METHODS: We examined retrospectively the results of 154 consecutive OGTTs in such patients performed using capillary whole blood.
RESULTS: With the 1985 WHO criteria. Forty-four point eight per cent of subjects (69 subjects, with 95% confidence intervals, 37-52.6%) had diabetes, 47.8% (33 subjects, 36-59.6%) had a normal fasting glucose, 31.2% (48 subjects, 23.9-38.5%) had impaired glucose tolerance (IGT) and 76% (117 subjects, 69.3-82.7%) had abnormal glucose tolerance. Applying the ADA criteria (fasting capillary whole blood only), 33.1% (51 subjects, 25.7-40.5%) had diabetes (a 26% relative reduction) and 11% (17 subjects, 6.1-15.9%) IFG, with 44.1% (68 subjects, 36.3-51.9%) having abnormal glucose metabolism (a 42% relative reduction). If the proposed 1998 WHO criteria were used, the number with diabetes increase to 48% (74 subjects, 40.1-55.9%) a 7.2% increase on the old criteria. 27.9% (43 subjects, 20.8-35%) had IGT, so the number with some degree of abnormal glucose metabolism remains unchanged. Use of the ADA criteria, considering only the fasting glucose as suggested, will result in a significant reduction in the diagnosis of diabetes and those with abnormal glucose metabolism.

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Mesh:

Year:  1999        PMID: 10220210     DOI: 10.1046/j.1464-5491.1999.00056.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  2 in total

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2.  Diagnostic accuracy of the American Diabetes Association criteria in the diagnosis of glucose intolerance among high-risk Omani subjects.

Authors:  Al-Bahrani Ali Ihsan; Bukhiet Charles; Bayoumi Raid; Al-Yahyaee Said Ali
Journal:  Ann Saudi Med       Date:  2004 May-Jun       Impact factor: 1.526

  2 in total

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