Literature DB >> 10219646

Steroids treatment of granulomatous hepatitis complicating Coxiella burnetii acute infection.

M Crespo1, B Sopeña, J Bordón, J de la Fuente, M Rubianes, C Martinez-Vázquez.   

Abstract

Granulomatous hepatitis associated with Coxiella burnetii acute infection has an adverse clinical course in some patients. Surprisingly, it does not respond to antibiotic but to steroids treatment. A hypersensitivity mechanism has been implicated. A case of granulomatous hepatitis complicating C. burnetii acute infection is reported, which was refractory to antibiotics but, as in four other cases previously reported, showed a complete response to steroids. This case was found to support findings that moderate doses of steroids can be useful in patients with granulomatous hepatitis complicating C. burnetii infection and showing no response to antibiotic treatment.

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Year:  1999        PMID： 10219646     DOI： 10.1007/bf02560514

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  8 in total

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Journal:  Eur J Epidemiol       Date:  1991-05       Impact factor: 8.082

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Journal:  Hum Pathol       Date:  1980-01       Impact factor: 3.466

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Authors:  L B Travis; W D Travis; C Y Li; R V Pierre
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  8 in total
  3 in total

1.  Q Fever endocarditis: does serology predict outcome?

Authors:  Arístides de Alarcón
Journal:  Curr Infect Dis Rep       Date:  2012-08       Impact factor: 3.725

2.  Circulating cytokines and procalcitonin in acute Q fever granulomatous hepatitis with poor response to antibiotic and short-course steroid therapy: a case report.

Authors:  Chung-Hsu Lai; Jiun-Nong Lin; Lin-Li Chang; Yen-Hsu Chen; Hsi-Hsun Lin
Journal:  BMC Infect Dis       Date:  2010-07-01       Impact factor: 3.090

3.  Prolonged pyrexia and hepatitis: Q fever.

Authors:  Caitlin Dugdale; Brian Chow; Evgeny Yakirevich; Erna Kojic; Bettina Knoll
Journal:  Am J Med       Date:  2014-06-12       Impact factor: 4.965
  3 in total

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