G M Bohigian1. 1. Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Abstract
BACKGROUND AND OBJECTIVE: To determine the incidence of culture-positive endophthalmitis after cataract surgery in an ambulatory surgical care center and to analyze the effectiveness of povidoneiodine solution in the preoperative preparation in preventing culture-positive endophthalmitis. PATIENTS AND METHODS: A retrospective series of 19,269 consecutive cases of cataract extraction with lens implantation over 12 years in an ambulatory care center was reviewed. RESULTS: Nine cases of culture-positive endophthalmitis occurred, for an incidence of 0.05%. The initial 4,740 cases (1985-1989) were performed without the use of povidone-iodine; the following 14,529 cases (1990-1996) were done using povidone-iodine. The incidence of culture-positive endophthalmitis was 0.08% and 0.03%, respectively. CONCLUSION: The incidence of culture-positive endophthalmitis in this series was very low. The use of 5% povidone-iodine, topically, appeared to be beneficial in reducing the incidence of culture-positive endophthalmitis after cataract extraction (P=0.24), but was not statistically significant in this retrospective series. Evaluation and methods to prevent endophthalmitis are difficult in retrospective clinical studies due to multiple variables and the rarity of this complication.
BACKGROUND AND OBJECTIVE: To determine the incidence of culture-positive endophthalmitis after cataract surgery in an ambulatory surgical care center and to analyze the effectiveness of povidoneiodine solution in the preoperative preparation in preventing culture-positive endophthalmitis. PATIENTS AND METHODS: A retrospective series of 19,269 consecutive cases of cataract extraction with lens implantation over 12 years in an ambulatory care center was reviewed. RESULTS: Nine cases of culture-positive endophthalmitis occurred, for an incidence of 0.05%. The initial 4,740 cases (1985-1989) were performed without the use of povidone-iodine; the following 14,529 cases (1990-1996) were done using povidone-iodine. The incidence of culture-positive endophthalmitis was 0.08% and 0.03%, respectively. CONCLUSION: The incidence of culture-positive endophthalmitis in this series was very low. The use of 5% povidone-iodine, topically, appeared to be beneficial in reducing the incidence of culture-positive endophthalmitis after cataract extraction (P=0.24), but was not statistically significant in this retrospective series. Evaluation and methods to prevent endophthalmitis are difficult in retrospective clinical studies due to multiple variables and the rarity of this complication.