| Literature DB >> 10218855 |
P D Kottaridis1, H Rees, G Smith, S F Garner, A R Perry, A J Peniket, A H Goldstone, S Mackinnon, W H Ouwehand.
Abstract
We report the case of a 32-year-old patient with ALL who developed autoimmune thrombocytopenia 2 months following allogeneic bone marrow transplantation. An IgM autoantibody against the platelet glycoprotein Ib/IX complex was observed. Treatment with high-dose steroids and intravenous immunoglobulin G failed to produce any benefit and the thrombocytopenia led to fatal gastrointestinal haemorrhage. The possible factors contributing to post-allograft thrombocytopenia and potential management strategies are discussed.Entities:
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Year: 1999 PMID： 10218855 DOI： 10.1038/sj.bmt.1701651
Source DB: PubMed Journal: Bone Marrow Transplant ISSN： 0268-3369 Impact factor: 5.483