| Literature DB >> 10218762 |
Abstract
Factor V is a large, multi-domain glycoprotein that exhibits both procoagulant and anticoagulant activity. Anti-factor V antibodies may develop by several mechanisms and, depending on their epitope specificity, may produce hemorrhagic or thromboembolic complications. The clinical laboratory is an essential component in diagnosing these antibodies, and therapeutic management depends on the predominant clinical manifestations.Entities:
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Year: 1999 PMID： 10218762 DOI： 10.1016/s0022-2143(99)90062-8
Source DB: PubMed Journal: J Lab Clin Med ISSN： 0022-2143