OBJECTIVE: To report on our series of encrusted cystopathy. METHODS: The clinical records of 37 patients (25 males, 67%; 12 females, 33%) with a histological diagnosis of encrusted cystopathy were reviewed. RESULTS: Only 11 patients (29.7%) met the classical criteria for alkaline encrusted cystitis. They had an initial or predisposing bladder lesion, irritative symptoms, passed calcareous material, a demonstrated or suspected urinary infection from ureolytic pathogens and alkaline urine. The remaining 26 patients (70.2%) with histologically demonstrated encrustations on the bladder wall did not meet the foregoing criteria. Fifty-seven percent of the patients had a previous history of bladder tumor resection and treatment with intravesical instillations. CONCLUSIONS: Alkaline encrusted cystopathy is an uncommon condition. Encrusting cystopathy can develop in the absence of ureolytic pathogens or alkaline urine. The bladder lesion on which the encrusting cystopathy is established, is determinant in the subsequent evolution.
OBJECTIVE: To report on our series of encrusted cystopathy. METHODS: The clinical records of 37 patients (25 males, 67%; 12 females, 33%) with a histological diagnosis of encrusted cystopathy were reviewed. RESULTS: Only 11 patients (29.7%) met the classical criteria for alkaline encrusted cystitis. They had an initial or predisposing bladder lesion, irritative symptoms, passed calcareous material, a demonstrated or suspected urinary infection from ureolytic pathogens and alkaline urine. The remaining 26 patients (70.2%) with histologically demonstrated encrustations on the bladder wall did not meet the foregoing criteria. Fifty-seven percent of the patients had a previous history of bladder tumor resection and treatment with intravesical instillations. CONCLUSIONS: Alkaline encrusted cystopathy is an uncommon condition. Encrusting cystopathy can develop in the absence of ureolytic pathogens or alkaline urine. The bladder lesion on which the encrusting cystopathy is established, is determinant in the subsequent evolution.
Authors: Tomislav M Jelic; Rod Roque; Uzay Yasar; Shayna B Tomchin; Jose M Serrato; Samuel G Deem; James P Tierney; Ho-Huang Chang Journal: Int J Nanomedicine Date: 2008