Literature DB >> 10218115

Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation.

D C Gadsby1, A C Nairn.   

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Year:  1999        PMID: 10218115     DOI: 10.1016/s1040-7952(99)80006-8

Source DB:  PubMed          Journal:  Adv Second Messenger Phosphoprotein Res        ISSN: 1040-7952


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  8 in total

1.  Functional reconstitution and channel activity measurements of purified wildtype and mutant CFTR protein.

Authors:  Paul D W Eckford; Canhui Li; Christine E Bear
Journal:  J Vis Exp       Date:  2015-03-09       Impact factor: 1.355

Review 2.  Cl⁻ channels in smooth muscle cells.

Authors:  Simon Bulley; Jonathan H Jaggar
Journal:  Pflugers Arch       Date:  2014-05       Impact factor: 3.657

3.  The glycine residues G551 and G1349 within the ATP-binding cassette signature motifs play critical roles in the activation and inhibition of cystic fibrosis transmembrane conductance regulator channels by phloxine B.

Authors:  Patricia Melin; Caroline Norez; Isabelle Callebaut; Frédéric Becq
Journal:  J Membr Biol       Date:  2006-04-07       Impact factor: 1.843

4.  How Phosphorylation and ATPase Activity Regulate Anion Flux though the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Authors:  Matthias Zwick; Cinzia Esposito; Manuel Hellstern; Anna Seelig
Journal:  J Biol Chem       Date:  2016-05-12       Impact factor: 5.157

5.  Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.

Authors:  Paul D W Eckford; Canhui Li; Mohabir Ramjeesingh; Christine E Bear
Journal:  J Biol Chem       Date:  2012-08-31       Impact factor: 5.157

6.  On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator.

Authors:  Ying-Chun Yu; Yoshiro Sohma; Tzyh-Chang Hwang
Journal:  J Physiol       Date:  2016-03-23       Impact factor: 5.182

7.  A macromolecular complex of beta 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA.

Authors:  Anjaparavanda P Naren; Bryan Cobb; Chunying Li; Koushik Roy; David Nelson; Ghanshyam D Heda; Jie Liao; Kevin L Kirk; Eric J Sorscher; John Hanrahan; John P Clancy
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-26       Impact factor: 11.205

8.  Spatial positioning of CFTR's pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway.

Authors:  Xiaolong Gao; Tzyh-Chang Hwang
Journal:  J Gen Physiol       Date:  2016-05       Impact factor: 4.086

  8 in total

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