| Literature DB >> 10217828 |
S Ugolini1, I Mondor, Q J Sattentau.
Abstract
HIV-1 attachment to host cells is generally considered to take place via high-affinity binding between CD4 and gp120. However, the binding of virion-associated gp120 to cellular CD4 is often weak, and most cell types that are permissive for HIV-1 infection express little CD4. Thus, other interactions between the virion and the cell surface could dominate the attachment process.Entities:
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Year: 1999 PMID： 10217828 DOI： 10.1016/s0966-842x(99)01474-2
Source DB: PubMed Journal: Trends Microbiol ISSN： 0966-842X Impact factor: 17.079