Literature DB >> 10217735

Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of penicillium sclerotigenum

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Abstract

A new benzodiazepine, sclerotigenin (1), was isolated from organic extracts of the sclerotia of Penicillium sclerotigenum (NRRL 3461) along with two known griseofulvin analogues. The structure of 1 was determined primarily by analysis of 1H NMR, 13C NMR, HMQC, and HMBC data. Compound 1 was the major component of the CH2Cl2 extract of P. sclerotigenum sclerotia and is responsible for most of the antiinsectan activity of the extract against the crop pest Helicoverpa zea.

Entities:  

Year:  1999        PMID： 10217735     DOI： 10.1021/np980511n

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  12 in total

Review 1.  Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks.

Authors:  Christopher T Walsh; Stuart W Haynes; Brian D Ames; Xue Gao; Yi Tang
Journal:  ACS Chem Biol       Date:  2013-06-04       Impact factor: 5.100

2.  Haenamindole and fumiquinazoline analogs from a fungicolous isolate of Penicillium lanosum.

Authors:  In Hyun Hwang; Yongsheng Che; Dale C Swenson; James B Gloer; Donald T Wicklow; Stephen W Peterson; Patrick F Dowd
Journal:  J Antibiot (Tokyo)       Date:  2016-06-22       Impact factor: 2.649

3.  Anthranilate-activating modules from fungal nonribosomal peptide assembly lines.

Authors:  Brian D Ames; Christopher T Walsh
Journal:  Biochemistry       Date:  2010-04-20       Impact factor: 3.162

4.  Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E.

Authors:  Stuart W Haynes; Xue Gao; Yi Tang; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2012-10-09       Impact factor: 15.419

5.  Fluorous-enhanced multicomponent reactions for making drug-like library scaffolds.

Authors:  Wei Zhang
Journal:  Comb Chem High Throughput Screen       Date:  2007-03       Impact factor: 1.339

6.  Quinazolinobenzodiazepine Derivatives, Novobenzomalvins A-C: Fibronectin Expression Regulators from Aspergillus novofumigatus.

Authors:  Kazuki Ishikawa; Tomoo Hosoe; Takeshi Itabashi; Fumiaki Sato; Hiroshi Wachi; Hiromasa Nagase; Takashi Yaguchi; Ken-Ichi Kawai
Journal:  Sci Pharm       Date:  2011-10-03

7.  Synthesis, anticonvulsant, sedative and anxiolytic activities of novel annulated pyrrolo[1,4]benzodiazepines.

Authors:  Kumaraswamy Sorra; Chien-Shu Chen; Chi-Fen Chang; Srinivas Pusuluri; Khagga Mukkanti; Chi-Rei Wu; Ta-Hsien Chuang
Journal:  Int J Mol Sci       Date:  2014-09-18       Impact factor: 5.923

8.  Polyphasic taxonomy of Aspergillus section Cervini.

Authors:  A J Chen; J Varga; J C Frisvad; X Z Jiang; R A Samson
Journal:  Stud Mycol       Date:  2016-11-09       Impact factor: 16.097

9.  Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones.

Authors:  Yong-Bin Wang; Sheng-Cai Zheng; Yu-Mei Hu; Bin Tan
Journal:  Nat Commun       Date:  2017-05-19       Impact factor: 14.919

10.  Cyclic Tetrapeptides with Synergistic Antifungal Activity from the Fungus Aspergillus westerdijkiae Using LC-MS/MS-Based Molecular Networking.

Authors:  Junjie Han; Hanying Wang; Rui Zhang; Huanqin Dai; Baosong Chen; Tao Wang; Jingzu Sun; Wenzhao Wang; Fuhang Song; Erwei Li; Zhitang Lyu; Hongwei Liu
Journal:  Antibiotics (Basel)       Date:  2022-01-27
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