Literature DB >> 1021449

Potentiation by taurine of the inotropic effect of ouabain and the content of intracellular Ca++ and taurine in the heart.

H I Iwata, S Fujimoto.   

Abstract

Under certain conditions, taurine (3.0mM) potentiated cardiac contractile response to ouabain in the normal medium. The potentiation by taurine was also observed in the low K+ medium, in which the positive inotropic effect of ouabain increased. The potentiation as seen in both media was, at least in part, due to the increase by taurine of Ca++ content in the heart. Taurine in the heart was not directly related to this potentiation.

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Year:  1976        PMID： 1021449     DOI： 10.1007/BF01924452

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Effect of taurine on epinephrine and digoxin induced irregularities of the dog heart.

Authors:  W O READ; J D WELTY
Journal:  J Pharmacol Exp Ther       Date:  1963-03       Impact factor: 4.030

2.  The taurine concentration of organs from fed and fasted rats.

Authors:  J AWAPARA
Journal:  J Biol Chem       Date:  1956-02       Impact factor: 5.157

3.  Effect of taurine on a muscle intracellular membrane.

Authors:  R Huxtable; R Bressler
Journal:  Biochim Biophys Acta       Date:  1973-11-16

Review 4.  Biochemistry and physiology of taurine and taurine derivatives.

Authors:  J G Jacobsen; L H Smith
Journal:  Physiol Rev       Date:  1968-04       Impact factor: 37.312

5.  Effect of taurine on calcium kinetics of guinea-pig heart.

Authors:  P Dolara; A Agresti; A Giotti; G Pasquini
Journal:  Eur J Pharmacol       Date:  1973-12       Impact factor: 4.432

6.  Factors that regulate ouabain-H3 accumulation by the isolated guinea-pig heart.

Authors:  S Dutta; B H Marks
Journal:  J Pharmacol Exp Ther       Date:  1969-12       Impact factor: 4.030

7.  Effect of taurine on responses to noradrenaline, acetylcholine and ouabain in isolated auricles from digitalized guinea pigs.

Authors:  S Fujimoto; H Iwata; Y Yoneda
Journal:  Jpn J Pharmacol       Date:  1976-02

8.  [Inhibitory effect of taurine on ouabain-induced arrythmia].

Authors:  S Fujimoto; H Iwata
Journal:  Nihon Yakurigaku Zasshi       Date:  1975-01

9.  Taurine concentrations in congestive heart failure.

Authors:  R Huxtable; R Bressler
Journal:  Science       Date:  1974-06-14       Impact factor: 47.728
  9 in total
  2 in total

1.  Inhibitory effect of taurine on decrease in the inotropic action of ouabain at high concentrations in isolated atria.

Authors:  S Fujimoto
Journal:  Experientia       Date:  1977-10-15

2.  Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health.

Authors:  James J DiNicolantonio; James H OKeefe; Mark F McCarty
Journal:  Open Heart       Date:  2017-05-22
  2 in total

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