Literature DB >> 10214478

The European Brain Injury Consortium survey of head injuries.

G D Murray1, G M Teasdale, R Braakman, F Cohadon, M Dearden, F Iannotti, A Karimi, F Lapierre, A Maas, J Ohman, L Persson, F Servadei, N Stocchetti, T Trojanowski, A Unterberg.   

Abstract

To provide a picture of contemporary practice, a survey was carried out of severely and moderately head injured patients admitted to 67 'neuro' centres in 12 European countries. 1,005 adult head injuries were recruited over a three month period. Sixty items of information on demography, clinical features, investigations, management and early complications were captured on a simple, two-page questionnaire and, information on outcome at six months on a third page. The median age of the subjects was 38 years, 74% were male and 51% injured in road traffic accidents; 57% of patients were transferred to the 'neuro' centre from another hospital. Assessment of clinical responsiveness was limited by the use of sedation and intubation and information from four early time points (pre-hospital, arrival at the Accident and Emergency department, post-resuscitation, and arrival at the 'neuro' unit) was combined to stratify the subjects as severe (58%), moderate (17%) or intermediate (19%). In 48% of patients classified the CT scan showed features of a 'mass lesion' and in 40% showed a subarachnoid haemorrhage. Fifty-five centres provided the data on outcome for 94% of the cases recruited in these centres six months after injury. 31% died, 3% were vegetative, 16% severely disabled, 20% moderately disabled and 31% had made a good recovery. Comparison of the data from different parts of Europe showed differences in the frequency of secondary transfer, cause of injury, occurrence of major extracranial injury, CT scan findings, intracranial operation, clinical severity of injury and utilisation of the components of intensive care and the occurrence of a favourable outcome, although the latter difference was not statistically significant when variations in the initial severity of injury were taken into account. The findings in the present survey are compared with newly analysed information for three previous large series: the International Data Bank involving the UK, the Netherlands and the USA, the North American Traumatic Coma Data Bank, and data from four centres in the UK. The comparisons showed substantial similarities and also differences that may reflect variations in policy for admission of the head injury to 'neuro' units, and evolution in methods of assessment, investigation and management. The effects of these differences on outcome requires further, rigorous prospective study.

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Year:  1999        PMID: 10214478     DOI: 10.1007/s007010050292

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN: 0001-6268            Impact factor:   2.216


  64 in total

1.  Clinical studies in severe traumatic brain injury: a controversial issue.

Authors:  Per-Olof Grände; Silvana Naredi
Journal:  Intensive Care Med       Date:  2002-02-09       Impact factor: 17.440

Review 2.  Clinical trials in head injury.

Authors:  Raj K Narayan; Mary Ellen Michel; Beth Ansell; Alex Baethmann; Anat Biegon; Michael B Bracken; M Ross Bullock; Sung C Choi; Guy L Clifton; Charles F Contant; William M Coplin; W Dalton Dietrich; Jamshid Ghajar; Sean M Grady; Robert G Grossman; Edward D Hall; William Heetderks; David A Hovda; Jack Jallo; Russell L Katz; Nachshon Knoller; Patrick M Kochanek; Andrew I Maas; Jeannine Majde; Donald W Marion; Anthony Marmarou; Lawrence F Marshall; Tracy K McIntosh; Emmy Miller; Noel Mohberg; J Paul Muizelaar; Lawrence H Pitts; Peter Quinn; Gad Riesenfeld; Claudia S Robertson; Kenneth I Strauss; Graham Teasdale; Nancy Temkin; Ronald Tuma; Charles Wade; Michael D Walker; Michael Weinrich; John Whyte; Jack Wilberger; A Byron Young; Lorraine Yurkewicz
Journal:  J Neurotrauma       Date:  2002-05       Impact factor: 5.269

3.  'Treat first, ask later?' Emergency research in acute neurology and neurotraumatology in the European Union.

Authors:  Erwin J O Kompanje; Andrew I R Maas
Journal:  Intensive Care Med       Date:  2003-11-21       Impact factor: 17.440

4.  New European directive on clinical trials: implications for traumatic head injury research.

Authors:  Nino Stocchetti; Mark Dearden; Abbi Karimi; Francoise Lapierre; Andrew Maas; Gordon D Murray; Juha Ohman; Lennart Persson; Franco Servadei; Tomasz Trojanowski; Andreas Unterberg
Journal:  Intensive Care Med       Date:  2004-01-16       Impact factor: 17.440

Review 5.  Traumatic brain injury in older adults.

Authors:  Richard B Ferrell; Kaloyan S Tanev
Journal:  Curr Psychiatry Rep       Date:  2002-10       Impact factor: 5.285

Review 6.  [Craniocerebral trauma. 2: Intra-axial injuries, secondary injuries].

Authors:  T Struffert; C Axmann; W Reith
Journal:  Radiologe       Date:  2003-11       Impact factor: 0.635

7.  Lessons from traumatic head injury for assessing functional status after brain tumour.

Authors:  J T Lindsay Wilson
Journal:  J Neurooncol       Date:  2012-02-11       Impact factor: 4.130

Review 8.  MDCT imaging of traumatic brain injury.

Authors:  Valentina Lolli; Martina Pezzullo; Isabelle Delpierre; Niloufar Sadeghi
Journal:  Br J Radiol       Date:  2016-01-05       Impact factor: 3.039

9.  Factors associated with the withdrawal of life-sustaining therapies in patients with severe traumatic brain injury: a multicenter cohort study.

Authors:  Nicolas Côte; Alexis F Turgeon; François Lauzier; Lynne Moore; Damon C Scales; Francis Bernard; Ryan Zarychanski; Karen E A Burns; Maureen O Meade; David Zygun; Jean-François Simard; Amélie Boutin; Jacques G Brochu; Dean A Fergusson
Journal:  Neurocrit Care       Date:  2013-02       Impact factor: 3.210

Review 10.  [Traumatic brain injury: impact on timing and modality of fracture care].

Authors:  P F Stahel; W Ertel; C E Heyde
Journal:  Orthopade       Date:  2005-09       Impact factor: 1.087

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