Literature DB >> 10213267

Enhancing the inhibitory effect of nicotinamide upon collagen II induced arthritis in mice using N-acetylcysteine.

H Kröger1, A Hauschild, M Ohde, K Bache, W P Voigt, W Ehrlich.   

Abstract

We could show that both nicotinamide and N-acetylcysteine inhibit collagen induced arthritis in mice. In the present paper, using lower doses of each, we applied combinations of these two substances. We were able to confirm potentiating effects of these combinations. These results may allow new perspectives for the therapy of arthritis to emerge.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10213267     DOI： 10.1023/a:1020284810976

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  6 in total

1.  Collagen-induced arthritis in the mouse.

Authors:  P H Wooley
Journal:  Methods Enzymol       Date:  1988       Impact factor: 1.600

2.  The therapeutic effect of a combination of cofpropamine, a caffeine derivative, and cyclophosphamide on the development of adjuvant arthritis of rats and collagen arthritis of mice.

Authors:  H Kröger; J Klosa; R Grätz; A Dietrich; W Ehrlich; A Wild
Journal:  Gen Pharmacol       Date:  1996-10

3.  Suppression of type II collagen-induced arthritis by N-acetyl-L-cysteine in mice.

Authors:  H Kröger; R Miesel; A Dietrich; M Ohde; S Altrichter; C Braun; H Ockenfels
Journal:  Gen Pharmacol       Date:  1997-10

4.  Synergistic effects of thalidomide and poly (ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice.

Authors:  H Kröger; R Miesel; A Dietrich; M Ohde; E Rajnavölgyi; H Ockenfels
Journal:  Inflammation       Date:  1996-04       Impact factor: 4.092

5.  Modulation of inflammatory arthritis by inhibition of poly(ADP ribose) polymerase.

Authors:  R Miesel; M Kurpisz; H Kröger
Journal:  Inflammation       Date:  1995-06       Impact factor: 4.092

6.  Effects of allopurinol on in vivo suppression of arthritis in mice and ex vivo modulation of phagocytic production of oxygen radicals in whole human blood.

Authors:  R Miesel; M Zuber; D Sanocka; R Graetz; H Kroeger
Journal:  Inflammation       Date:  1994-12       Impact factor: 4.092
  6 in total
  4 in total

Review 1.  Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide.

Authors:  Faqi Li; Zhao Zhong Chong; Kenneth Maiese
Journal:  Curr Med Chem       Date:  2006       Impact factor: 4.530

2.  N-Acetylcysteine enhances the action of anti-inflammatory drugs as suppressors of prostaglandin production in monocytes.

Authors:  Erica Hoffer; Yelena Baum; A Menahem Nahir
Journal:  Mediators Inflamm       Date:  2002-10       Impact factor: 4.711

Review 3.  The vitamin nicotinamide: translating nutrition into clinical care.

Authors:  Kenneth Maiese; Zhao Zhong Chong; Jinling Hou; Yan Chen Shang
Journal:  Molecules       Date:  2009-09-09       Impact factor: 4.411

4.  Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis.

Authors:  Kazim Sahin; Osman Kucuk; Cemal Orhan; Mehmet Tuzcu; Ali Said Durmus; Ibrahim Hanifi Ozercan; Nurhan Sahin; Vijaya Juturu
Journal:  Sci Rep       Date:  2021-07-19       Impact factor: 4.379
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.