Literature DB >> 10211480

Progressive hippocampal atrophy in chronic intractable temporal lobe epilepsy.

T J O'Brien1, E L So, F B Meyer, J E Parisi, C R Jack.   

Abstract

We report on a 28-year-old man with long-standing intractable complex partial and secondary generalized seizures, whose magnetic resonance imaging scans 4 years apart documented progressive decrease in the left hippocampal volume. Left anterior temporal lobectomy with amygdalohippocampectomy rendered the patient seizure free at 12 months' follow-up. The findings demonstrate that patients with uncontrolled temporal lobe seizures may develop progressive atrophy of the hippocampus, in the absence of status epilepticus.

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Year:  1999        PMID: 10211480

Source DB:  PubMed          Journal:  Ann Neurol        ISSN: 0364-5134            Impact factor:   10.422


  8 in total

1.  MR imaging volumetry of subcortical structures and cerebellar hemispheres in temporal lobe epilepsy.

Authors:  C A Szabó; J L Lancaster; S Lee; J-H Xiong; C Cook; B N Mayes; P T Fox
Journal:  AJNR Am J Neuroradiol       Date:  2006 Nov-Dec       Impact factor: 3.825

2.  A cerebral network reflecting reorganization in medial temporal lobe epilepsy.

Authors:  Gregory D Cascino
Journal:  Epilepsy Curr       Date:  2006 Mar-Apr       Impact factor: 7.500

3.  "Connectionology" provides further evidence for nociferous epileptic cortex.

Authors:  Frank Gilliam
Journal:  Epilepsy Curr       Date:  2014-07       Impact factor: 7.500

4.  Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single "cryptic" episode of focal hippocampal excitation in awake rats.

Authors:  Braxton A Norwood; Argyle V Bumanglag; Francesco Osculati; Andrea Sbarbati; Pasquina Marzola; Elena Nicolato; Paolo F Fabene; Robert S Sloviter
Journal:  J Comp Neurol       Date:  2010-08-15       Impact factor: 3.215

Review 5.  Febrile seizures and mechanisms of epileptogenesis: insights from an animal model.

Authors:  Roland A Bender; Celine Dubé; Tallie Z Baram
Journal:  Adv Exp Med Biol       Date:  2004       Impact factor: 2.622

Review 6.  Advances in neuroimaging: management of partial epileptic syndromes.

Authors:  Barbara Schäuble; Gregory D Cascino
Journal:  Neurosurg Rev       Date:  2003-08-22       Impact factor: 3.042

7.  Chronic Epilepsy Does Not Cause Measurable Structural Changes on MRI.

Authors:  Andres M. Kanner
Journal:  Epilepsy Curr       Date:  2003-01       Impact factor: 7.872

8.  'MRI-negative PET-positive' temporal lobe epilepsy (TLE) and mesial TLE differ with quantitative MRI and PET: a case control study.

Authors:  Ross P Carne; Terence J O'Brien; Christine J Kilpatrick; Lachlan R Macgregor; Lucas Litewka; Rodney J Hicks; Mark J Cook
Journal:  BMC Neurol       Date:  2007-06-24       Impact factor: 2.474

  8 in total

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