| Literature DB >> 1021092 |
R G Dickinson, J E O'Hagan, M Schotz, K C Binnington, M P Hegarty.
Abstract
Previous studies of saliva from engorged female cattle ticks revealed a component which induced contration of some isolated smooth muscles. Fractionation and further characterisation have shown that this substance is of the "slow-reacting" type, but that it is neither a bradykinin nor slow-reacting substance of anaphylaxis. The substance is deactivated by incubation with 15-hydroxprostaglandin dehydrogenase and its pharmacological properties also support its classification as a prostaglandin. A second pharmacologically-active component has now been found in the saliva but has not yet been characterised.Entities:
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Year: 1976 PMID: 1021092 DOI: 10.1038/icb.1976.48
Source DB: PubMed Journal: Aust J Exp Biol Med Sci ISSN: 0004-945X