Literature DB >> 10209928

Solitary cellular schwannoma (neurilemmoma) showing malignant changes: evaluation through magnetic resonance imaging (M.R.I.), surgical intervention, and histopathology.

V N Sehgal1, R L Gupta, A Bhatia, S Kumar, S Jain, V Kapoor.   

Abstract

Schwannoma (neurilemmoma) are common benign tumors arising from the peripheral nerve sheath. Malignant transformation is uncommon. A unique case showing such a transformation is reported highlighting the roles of magnetic resonance imaging, surgical intervention, and histopathology. The case was thoroughly investigated by learning the details of the sequence of events leading to the current status. The evaluation was made through magnetic resonance imaging. In addition, computed tomography and conventional radiography were used to locate any foci of calcification. Subsequently, the tumor's gross and microscopic morphology was defined by surgical intervention and histopathology. Malignant schwannoma of the left leg occupying the entire calf is extremely uncommon. Only ten cases have been reported thus far, including the current one from the Indian subcontinent. Malignant transformation in a schwannoma differs significantly from malignant nerve sheath tumors (erroneously called malignant schwannomas). An endeavour has been made to differentiate malignant transformation in schwannoma from other malignant peripheral nerve sheath tumors. An innovation in this direction is magnetic resonance imaging. This investigate procedure is imperative in such situations, along with surgery and histopathology, which may also help in classifying the condition.

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Year:  1999        PMID: 10209928     DOI: 10.1111/j.1346-8138.1999.tb03453.x

Source DB:  PubMed          Journal:  J Dermatol        ISSN: 0385-2407            Impact factor:   4.005


  2 in total

1.  Perineal schwannoma.

Authors:  Sebastiano Pantè; Maria-Luisa Terranova; Grazia Leonello; Francesco Fedele; Giorgio Ascenti; Ciro Famulari
Journal:  Can J Surg       Date:  2009-02       Impact factor: 2.089

2.  Sciatica due to Schwannoma at the Sciatic Notch.

Authors:  Yavuz Haspolat; Feyza Unlu Ozkan; Ismail Turkmen; Bahattin Kemah; Yalcin Turhan; Serhan Sarar; Korhan Ozkan
Journal:  Case Rep Orthop       Date:  2013-05-19
  2 in total

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