| Literature DB >> 10206545 |
S M Husbands1, S W Breeden, K Grivas, J W Lewis.
Abstract
A series of furanomorphides were synthesised as ring-constrained analogues of buprenorphine and related orvinols. Evaluation in binding and functional assays has shown that the furanomorphides have reduced efficacy at the mu opioid receptor compared to the orvinols.Entities:
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Year: 1999 PMID： 10206545 DOI： 10.1016/s0960-894x(99)00085-2
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823