Virtual bronchoscopy.

Three-dimensional endoluminal tracheobronchial simulations can be derived successfully from thoracic helical CT scans, and can reproduce the appearances of major endobronchial abnormalities confirmed during FB. The prospects of ever-faster CT scanners (capable of submillimeter resolution) merged with greater computer power make it likely that current versions of virtual bronchoscopy images will seem primitive in the future. Initial descriptive reports suggest great potential, but the startling visual appeal of these 3-D portrayals of a patient's airway and mediastinal anatomy and the prospects of exploring this information in real time do not establish its clinical role. Such virtual bronchoscopy findings are generally predictable on the basis of currently available axial CT images alone. The extent to which these 3-D endobronchial renderings improve the already high predictive values of CT requires critical study. In their patients with lung cancer Cicero et al observed that neither the staging nor diagnosis was modified substantially, but virtual bronchoscopy contributed to enhanced understanding of the pathology of the neoplastic process. Whether this added perspective translates to tangible benefits for patients is an intriguing possibility that has yet to be proved. The unique 3-D endobronchial view may offer particular advantages in some individuals and contribute to the patient's noninvasive evaluation. Because of the already high yield of conventional CT, diagnostic yield alone is not likely to be the sole best measure of this evolving technology. Accordingly, future multidisciplinary research investigations will also need to prospectively address nuances of decision-making and measure appropriate patient outcomes. In these efforts the active dialogue between chest clinician and radiologist will remain essential to defining and realizing the true potential of virtual bronchoscopy.