Literature DB >> 10203773

The complexities of DNA computation.

J C Cox1, D S Cohen, A D Ellington.   

Abstract

Over the past few years, a handful of insightful researchers have bridged the gap between biological computing theory and actual DNA-based computation. By using ingenious encoding techniques and clever molecular-biological manipulations, simple versions of computationally complex problems have been experimentally approached or resolved. However, the technical problems revealed during the execution of these scientific set pieces make it unlikely that DNA will ever rival silicon for the solution of any real-world problem.

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Year:  1999        PMID: 10203773     DOI: 10.1016/s0167-7799(99)01312-8

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  4 in total

1.  Phosphorylation at 5' end of guanosine stretches inhibits dimerization of G-quadruplexes and formation of a G-quadruplex interferes with the enzymatic activities of DNA enzymes.

Authors:  M Khabir Uddin; Yoshio Kato; Yasuomi Takagi; Toshiyasu Mikuma; Kazunari Taira
Journal:  Nucleic Acids Res       Date:  2004-08-27       Impact factor: 16.971

Review 2.  Artificial Molecular Machines.

Authors:  Sundus Erbas-Cakmak; David A Leigh; Charlie T McTernan; Alina L Nussbaumer
Journal:  Chem Rev       Date:  2015-09-08       Impact factor: 60.622

3.  Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme.

Authors:  Nathan C Gianneschi; M Reza Ghadiri
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

4.  A mechanical Turing machine: blueprint for a biomolecular computer.

Authors:  Ehud Shapiro
Journal:  Interface Focus       Date:  2012-03-21       Impact factor: 3.906

  4 in total

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