Literature DB >> 10201596

Association of high-dose intravenous methylprednisolone with reversal of blindness from lightning in two patients.

M E Norman1, B R Younge.   

Abstract

OBJECTIVE: To report possibly beneficial effects of treatment with high-dose corticosteroids given intravenously to two patients with loss of vision after lightning strikes.
DESIGN: Case reports. PARTICIPANTS: Two patients who suffered the effects of a lightning strike. INTERVENTION: High-dose intravenous methylprednisolone (NASCIS-2 Protocol). MAIN OUTCOME MEASURES: Vision recovery, pupil responses, and optic nerve appearance.
RESULTS: One patient had unilateral ophthalmoscopically visible abnormality with light perception vision and a relative afferent defect in that eye; vision recovered to 20/25. The other patient had no light perception, nonreactive pupils, and normal fundus examinations in both eyes; vision recovered bilaterally to normal (20/20).
CONCLUSIONS: High-dose intravenous corticosteroid treatment in these patients may have had a role in their visual recovery.

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Year:  1999        PMID: 10201596     DOI: 10.1016/S0161-6420(99)90160-4

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  1 in total

Review 1.  Neurological and neuropsychological consequences of electrical and lightning shock: review and theories of causation.

Authors:  Christopher J Andrews; Andrew D Reisner
Journal:  Neural Regen Res       Date:  2017-05       Impact factor: 5.135

  1 in total

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