Literature DB >> 10201416

Cervical spondylotic myelopathy in elderly people: a high incidence of conduction block at C3-4 or C4-5.

T Tani1, H Yamamoto, J Kimura.   

Abstract

OBJECTIVES: To precisely localise the site of conduction block in elderly patients with cervical spondylotic myelopathy in the presence of multilevel compression shown by MRI.
METHODS: A total of 44 patients aged 65 and older underwent serial intervertebral recording of spinal somatosensory evoked potentials (SSEPs) from either the intervertebral disc or the ligamentum flavum after epidural stimulation. The site of conduction block identified by abrupt reduction in size of the negative peak was designated as the 0 level with the other levels numbered in order of distance assigning a minus sign caudally.
RESULTS: A single site of focal conduction block was disclosed in 42 patients, 23 (55%) at C3-4, 17 (40%) at C4-5, and two (5%) at C5-6. At these levels (0), the amplitude of the negative component was reduced (p<0.0001) to 29% and the area to 22%, with a concomitant increase (p<0.0001) of the initial positive component to 150% in amplitude and 293% in area as compared to the-2 level which was taken as the baseline (100%).
CONCLUSIONS: A high incidence (95%) of focal conduction block at C3-4 or C4-5 with normal conduction at C5-6 and C6-7 characterises cervical spondylotic myelopathy in elderly people. Incremental SSEP studies documenting the site of conduction block will help exclude clinically silent cord compression, directing the surgical intervention to the appropriate level of concern.

Entities:  

Mesh:

Year:  1999        PMID: 10201416      PMCID: PMC1736286          DOI: 10.1136/jnnp.66.4.456

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  45 in total

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2.  Waveform analysis of spinal somatosensory evoked potential: paradoxically enhanced negative peaks immediately caudal to the site of conduction block.

Authors:  T Tani; T Ushida; H Yamamoto; J Kimura
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1998-07

3.  The effects of experimental demyelination on conduction in the central nervous system.

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Journal:  Brain       Date:  1970       Impact factor: 13.501

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Authors:  A R Taylor; D P Byrnes
Journal:  Brain       Date:  1974-09       Impact factor: 13.501

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Authors:  K Shimoji; H Higashi; T Kano
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1971-03

6.  Relief of pain by anterior cervical-spine fusion for spondylosis. A report of sixty-five patients.

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Journal:  J Bone Joint Surg Am       Date:  1973-04       Impact factor: 5.284

7.  The pathogenesis of the spinal cord disorder associated with cervical spondylosis.

Authors:  S Nurick
Journal:  Brain       Date:  1972       Impact factor: 13.501

8.  Hand wasting in spondylotic high cord compression: an electromyographic study.

Authors:  R J Stark; C Kennard; M Swash
Journal:  Ann Neurol       Date:  1981-01       Impact factor: 10.422

9.  The carpal tunnel syndrome: localization of conduction abnormalities within the distal segment of the median nerve.

Authors:  J Kimura
Journal:  Brain       Date:  1979-09       Impact factor: 13.501

10.  Anterior surgery for cervical disc disease. Part 2: Treatment of cervical spondylotic myelopathy in 32 cases.

Authors:  L D Lunsford; D J Bissonette; D S Zorub
Journal:  J Neurosurg       Date:  1980-07       Impact factor: 5.115

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  8 in total

1.  The effects of surgery on locomotion in elderly patients with cervical spondylotic myelopathy.

Authors:  Go Yoshida; Tokumi Kanemura; Yoshimoto Ishikawa; Akiyuki Matsumoto; Zenya Ito; Ryoji Tauchi; Akio Muramoto; Yukihiro Matsuyama; Naoki Ishiguro
Journal:  Eur Spine J       Date:  2013-08-18       Impact factor: 3.134

2.  Utility of the central motor conduction time recorded from the abductor pollicis brevis and the abductor digiti minimi muscles in patients with C6-7 myelopathy.

Authors:  Yasuaki Imajo; Tsukasa Kanchiku; Hidenori Suzuki; Masahiro Funaba; Norihiro Nishida; Toshihiko Taguchi
Journal:  J Spinal Cord Med       Date:  2017-05-17       Impact factor: 1.985

3.  Characteristics of C6-7 myelopathy: assessment of clinical symptoms and electrophysiological findings.

Authors:  M Funaba; T Kanchiku; Y Imajo; H Suzuki; Y Yoshida; N Nishida; K Fujimoto; T Taguchi
Journal:  Spinal Cord       Date:  2015-11-17       Impact factor: 2.772

4.  Upper thoracic-spine disc degeneration in patients with cervical pain.

Authors:  Estanislao Arana; Luis Martí-Bonmatí; Enrique Mollá; Salvador Costa
Journal:  Skeletal Radiol       Date:  2003-10-22       Impact factor: 2.199

5.  Biomechanical analysis of cervical spondylotic myelopathy: the influence of dynamic factors and morphometry of the spinal cord.

Authors:  Norihiro Nishida; Yoshihiko Kato; Yasuaki Imajo; Syunichi Kawano; Toshihiko Taguchi
Journal:  J Spinal Cord Med       Date:  2012-07       Impact factor: 1.985

6.  Effects of differences in age and body height on normal values of central motor conduction time determined by F-waves.

Authors:  Yasuaki Imajo; Tsukasa Kanchiku; Hidenori Suzuki; Yuichiro Yoshida; Masahiro Funaba; Norihiro Nishida; Kazuhiro Fujimoto; Toshihiko Taguchi
Journal:  J Spinal Cord Med       Date:  2015-12-14       Impact factor: 1.985

7.  Anterior Surgical Techniques for Cervical Spondylotic Myelopathy: WFNS Spine Committee Recommendations.

Authors:  Harsh Deora; Se-Hoon Kim; Sanjay Behari; Satish Rudrappa; Vedantam Rajshekhar; Mehmet Zileli; Jutty K B C Parthiban
Journal:  Neurospine       Date:  2019-09-30

8.  Magnetic motor evoked potentials of cervical muscles in horses.

Authors:  Joke Rijckaert; Bart Pardon; Luc Van Ham; Philip Joosten; Gunther van Loon; Piet Deprez
Journal:  BMC Vet Res       Date:  2018-09-24       Impact factor: 2.741

  8 in total

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