| Literature DB >> 10200949 |
A Inui1.
Abstract
Anorexia and body weight loss are characteristic of many diseases, including cancer and AIDS. Recent studies indicate that inflammatory cytokines, such as interleukin 1, the interleukin 6 subfamily and tumor necrosis factor, induce anorexia and cachexia by inhibiting the normal adaptive feeding response to energy deficits. Here, I discuss the evidence for and against a central role for neuropeptide Y and leptin in anorexia and cachexia.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10200949 DOI： 10.1016/s1357-4310(98)01395-1
Source DB: PubMed Journal: Mol Med Today ISSN： 1357-4310