The effect of vaccines and antimicrobials on the formation of injection site lesions in subprimals of experimentally injected beef calves.

Two hundred and thirty-nine beef calves were used to determine the occurrence of injection site lesions at slaughter (16 to 17 mo of age) following the use of 3 different 8-way clostridial bacterins, a 4-way viral respiratory vaccine, various long-acting oxytetracycline preparations, florfenicol, ceftiofur, and trimethoprim-sulfa when injected in the top hip (top butt), thigh (round), or neck (blade) of calves at 2 to 3 or 5 to 7 mo of age. The occurrence of lesions varied by product, route of administration, and location of injection. The number of steaks affected with lesions, the trim weight of lesions, the histological class of lesions, and the economic losses from trim are described.