Literature DB >> 1020055

Ultrastructural changes produced in cultured, adriamycin-treated myocardial cells.

A Necco, T Dasdia, S Cozzi, M Ferraguti.   

Abstract

The ultrastructural evaluation of the early alterations adriamycin-induced on cultured mice heart cells is reported. The major effects are hypertrophy of the sarcoplasmic reticulum and a market increase of the number and total extension of the gap junctions. These findings are discussed in the light of the information available in the literature.

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Year:  1976        PMID: 1020055     DOI: 10.1177/030089167606200508

Source DB:  PubMed          Journal:  Tumori        ISSN: 0300-8916


  2 in total

Review 1.  Doxorubicin effects on contractile structures and molecules.

Authors:  R Colombo; A Milzani; A Necco; G Vailati
Journal:  Cytotechnology       Date:  1990-01       Impact factor: 2.058

2.  Similar changes in cardiac morphology and DNA synthesis induced by doxorubicin and 4'-epi-doxorubicin.

Authors:  K Wassermann; K Mølgaard; E Steiness
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

  2 in total

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