| Literature DB >> 10198627 |
C Terré1, I Garcia, J N Bastie, D Mayeur, L Decombe, P Gruyer, R Berger, S Castaigne.
Abstract
We report a case of chronic neutrophilic leukemia (CNL) in a 68-year-old man. Karyotype showed a clonal abnormality, never described before in CNL: 46,XY,del(11)(q23). Southern blot analysis of the MLL gene did not reveal any rearrangement, and reverse transcriptase polymerase chain reaction (RT-PCR) analysis did not show any fusion of BCR-ABL. Treatment with hydroxyurea and cytosine arabisonide was ineffective.Entities:
Mesh：
Year: 1999 PMID： 10198627 DOI： 10.1016/s0165-4608(98)00177-0
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608