RATIONALE AND OBJECTIVES: To determine and analyze the most important error sources in lung CT densitometry in vivo. METHODS: The authors examined the influences of CT acquisition errors, physiologic changes, and image segmentation errors on lung densitometry. Among others, spatial dependency and long-term reproducibility of the density measurements of blood and air were examined over a period of 4 years in a group of 28 patients with pulmonary emphysema. These results were related to the measured lung densities in this group. RESULTS: The density measurement of blood and air is strongly dependent on the position in the thorax. Despite full-scanner calibrations, x-ray tube replacement can induce a significant increase in measured blood density. CONCLUSIONS: A change in a lung density parameter over time can actually be the result of tube replacement or changing blood density. A simple postprocessing technique can correct for these changes.
RATIONALE AND OBJECTIVES: To determine and analyze the most important error sources in lung CT densitometry in vivo. METHODS: The authors examined the influences of CT acquisition errors, physiologic changes, and image segmentation errors on lung densitometry. Among others, spatial dependency and long-term reproducibility of the density measurements of blood and air were examined over a period of 4 years in a group of 28 patients with pulmonary emphysema. These results were related to the measured lung densities in this group. RESULTS: The density measurement of blood and air is strongly dependent on the position in the thorax. Despite full-scanner calibrations, x-ray tube replacement can induce a significant increase in measured blood density. CONCLUSIONS: A change in a lung density parameter over time can actually be the result of tube replacement or changing blood density. A simple postprocessing technique can correct for these changes.
Authors: Sujal R Desai; David M Hansell; Amanda Walker; Sharon L S MacDonald; François Chabat; Athol U Wells Journal: Eur Radiol Date: 2006-08-29 Impact factor: 5.315
Authors: Song Soo Kim; Joon Beom Seo; Ho Yun Lee; Dipti V Nevrekar; Anna V Forssen; James D Crapo; Joyce D Schroeder; David A Lynch Journal: Radiology Date: 2012-12-06 Impact factor: 11.105
Authors: Jennifer L Boes; Maria Bule; Benjamin A Hoff; Ryan Chamberlain; David A Lynch; Jadranka Stojanovska; Fernando J Martinez; Meilan K Han; Ella A Kazerooni; Brian D Ross; Craig J Galbán Journal: Tomography Date: 2015-09