Literature DB >> 10196342

Oncogene activation in myeloid leukemias by Graffi murine leukemia virus proviral integration.

C Denicourt1, E Edouard, E Rassart.   

Abstract

The Graffi murine leukemia virus (MuLV) is a nondefective retrovirus that induces granulocytic leukemia in BALB/c and NFS mice. To identify genes involved in Graffi MuLV-induced granulocytic leukemia, tumor cell DNAs were examined for genetic alterations at loci described as common proviral integration sites in MuLV-induced myeloid, lymphoid, and erythroid leukemias. Southern blot analysis revealed rearrangements in c-myc, Fli-1, Pim-1, and Spi-1/PU.1 genes in 20, 10, 3.3, and 3.3% of the tumors tested, respectively. These results demonstrate for the first time the involvement of those genes in granulocytic leukemia.

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Year:  1999        PMID： 10196342      PMCID： PMC104225     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  48 in total

1.  His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia.

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Journal:  Oncogene       Date:  1991-11       Impact factor: 9.867

Review 2.  The role of c-myc in cell growth.

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Journal:  Curr Opin Genet Dev       Date:  1993-02       Impact factor: 5.578

Review 3.  Insertional mutagenesis and the transformation of hematopoietic stem cells.

Authors:  D S Askew; C Bartholomew; J N Ihle
Journal:  Hematol Pathol       Date:  1993

4.  Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

Authors:  E W Scott; M C Simon; J Anastasi; H Singh
Journal:  Science       Date:  1994-09-09       Impact factor: 47.728

5.  Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53.

Authors:  J R Jenkins; K Rudge; S Redmond; A Wade-Evans
Journal:  Nucleic Acids Res       Date:  1984-07-25       Impact factor: 16.971

6.  Expression and DNA rearrangement of proto-oncogenes in Cas-Br-E-induced non-T-, non-B-cell leukemias.

Authors:  D Bergeron; J Houde; L Poliquin; B Barbeau; E Rassart
Journal:  Leukemia       Date:  1993-07       Impact factor: 11.528

7.  Graffi murine leukemia virus: molecular cloning and characterization of the myeloid leukemia-inducing agent.

Authors:  M Ru; C Shustik; E Rassart
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103

8.  10A1 MuLV induces a murine leukemia that expresses hematopoietic stem cell markers by a mechanism that includes fli-1 integration.

Authors:  D E Ott; J Keller; A Rein
Journal:  Virology       Date:  1994-12       Impact factor: 3.616

9.  Regulation of the proto-oncogenes c-sis, c-fos, c-myc and c-myb in acute myeloid leukemias.

Authors:  C P Strassburg; V Neubauer; H Poliwoda; T Benter
Journal:  Neoplasma       Date:  1992       Impact factor: 2.575

10.  Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B.

Authors:  H M Chen; P Zhang; M T Voso; S Hohaus; D A Gonzalez; C K Glass; D E Zhang; D G Tenen
Journal:  Blood       Date:  1995-05-15       Impact factor: 22.113
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  10 in total

1.  Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.

Authors:  Omar Moussa; Amanda C LaRue; Romeo S Abangan; Christopher R Williams; Xian K Zhang; Masahiro Masuya; Yong Z Gong; Demetri D Spyropoulos; Makio Ogawa; Gary Gilkeson; Dennis K Watson
Journal:  Mol Cell Biol       Date:  2010-09-07       Impact factor: 4.272

2.  Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair.

Authors:  Anne Ahlmann Nielsen; Annette Balle Sørensen; Jörg Schmidt; Finn Skou Pedersen
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

3.  Gris1, a new common integration site in Graffi murine leukemia virus-induced leukemias: overexpression of a truncated cyclin D2 due to alternative splicing.

Authors:  Catherine Denicourt; Christine A Kozak; Eric Rassart
Journal:  J Virol       Date:  2003-01       Impact factor: 5.103

4.  Introduction of a cis-acting mutation in the capsid-coding gene of moloney murine leukemia virus extends its leukemogenic properties.

Authors:  M Audit; J Déjardin; B Hohl; C Sidobre; T J Hope; M Mougel; M Sitbon
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

5.  Negative and translation termination-dependent positive control of FLI-1 protein synthesis by conserved overlapping 5' upstream open reading frames in Fli-1 mRNA.

Authors:  S Sarrazin; J Starck; C Gonnet; A Doubeikovski; F Melet; F Morle
Journal:  Mol Cell Biol       Date:  2000-05       Impact factor: 4.272

6.  Importance of receptor usage, Fli1 activation, and mouse strain for the stem cell specificity of 10A1 murine leukemia virus leukemogenicity.

Authors:  Michaela Rodenburg; Meike Fischer; Afra Engelmann; Stephanie O Harbers; Marion Ziegler; Jürgen Löhler; Carol Stocking
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

7.  Large-scale identification of disease genes involved in acute myeloid leukemia.

Authors:  Stefan J Erkeland; Marijke Valkhof; Claudia Heijmans-Antonissen; Antoinette van Hoven-Beijen; Ruud Delwel; Mirjam H A Hermans; Ivo P Touw
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

8.  Identification of GPM6A and GPM6B as potential new human lymphoid leukemia-associated oncogenes.

Authors:  Cyndia Charfi; Elsy Edouard; Eric Rassart
Journal:  Cell Oncol (Dordr)       Date:  2014-06-12       Impact factor: 6.730

Review 9.  Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens.

Authors:  Enara Aguirre; Oliver Renner; Maja Narlik-Grassow; Carmen Blanco-Aparicio
Journal:  Front Oncol       Date:  2014-05-15       Impact factor: 6.244

10.  Gene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus.

Authors:  Veronique Voisin; Philippe Legault; Diana Paulina Salazar Ospina; Yaacov Ben-David; Eric Rassart
Journal:  BMC Med Genomics       Date:  2010-01-26       Impact factor: 3.063
  10 in total

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