| Literature DB >> 10195870 |
I Sasagawa1, Y Kubota, T Nakada, H Suzuki, J Hirano, O Sugano, H Kato, A Imamura, K Mastushita, Y Onmura, M Saito, M Adachi.
Abstract
Serum concentrations of luteinizing hormone (LH), testosterone, prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA) were measured in 16 patients with advanced prostatic cancer before and after treatment with luteinizing hormone-releasing hormone (LHRH) analogue. An initial rise of serum LH and testosterone levels was observed on day 2 of the treatment. Subsequently, serum concentrations of PAP and PSA showed a transient increase on day 5 of the treatment. This indicates that LHRH analogues had better be given in combination with antiandrogens in patients with metastatic carcinoma of the prostate.Entities:
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Year: 1998 PMID: 10195870 DOI: 10.1007/bf02564863
Source DB: PubMed Journal: Int Urol Nephrol ISSN: 0301-1623 Impact factor: 2.370