| Literature DB >> 10194868 |
Abstract
The expression of the murine Prl-1 protein tyrosine phosphatase gene was examined in normal embryos from E10.5 through E18.5. Prl-1 mRNA was detected in the brain, neural tube, and dorsal root ganglia, and in several non-neuronal tissues, including the skeletal system. Heart and skeletal muscle were consistently negative. At E13.5, Prl-1 was expressed in the condensing prechondrogenic cells of the vertebrae, whereas at E18.5, Prl-1 mRNA was localized to the hypertrophic chondrocytes. The dynamic expression of Prl-1 during cartilage differentiation may suggest a functional role in skeletal development.Entities:
Mesh:
Substances:
Year: 1999 PMID: 10194868 DOI: 10.1002/(sici)1097-010x(19990501)283:6<612::aid-jez14>3.3.co;2-o
Source DB: PubMed Journal: J Exp Zool ISSN: 0022-104X