Literature DB >> 10193327

How to improve low lymph node recovery rates from axillary clearance specimens of breast cancer. A short-term audit.

G Cserni1.   

Abstract

AIM: To implement an audit scheme to increase the lymph node yield from axillary clearance specimens.
METHODS: Two pathologists cut up each specimen after weighing it. The number of nodes and the dimensions of the largest and smallest nodes were recorded, together with the number of non-lymph node structures recovered. Fifty consecutive audited cases were compared with 50 consecutive cases assessed before the audit process.
RESULTS: It proved possible to increase the median number of lymph nodes from 10 to 22. There was an obvious learning period, during which the number of nodes recovered during the second pathologist's cut-up gradually decreased, while the total number remained relatively constant. The increase in lymph node yield resulted from the recovery of smaller nodes. The identification of lymph nodes also improved, and fewer non-lymph node structures were recovered by the end of the study.
CONCLUSIONS: Such an audit scheme can be recommended for all institutions where the lymph node yield of axillary clearance specimens seems suboptimal. The relevance of recovering more nodes remains to be determined; from this small series, it seems to have no clinical impact.

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Year:  1998        PMID: 10193327      PMCID: PMC500980          DOI: 10.1136/jcp.51.11.846

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  9 in total

1.  Total mastectomy and partial axillary dissection.

Authors:  B Cady
Journal:  Surg Clin North Am       Date:  1973-04       Impact factor: 2.741

2.  Number of lymph nodes examined and the prognosis of breast carcinoma.

Authors:  B Fisher; N H Slack
Journal:  Surg Gynecol Obstet       Date:  1970-07

3.  Axillary sampling and the risk of erroneous staging of breast cancer. An analysis of 960 consecutive patients.

Authors:  O Mathiesen; J Carl; O Bonderup; J Panduro
Journal:  Acta Oncol       Date:  1990       Impact factor: 4.089

4.  Audit of complete axillary dissection in early breast cancer.

Authors:  J V Reynolds; P Mercer; E W McDermott; S Cross; M Stokes; D Murphy; N J O'Higgins
Journal:  Eur J Cancer       Date:  1994       Impact factor: 9.162

5.  Measuring melanomas: the Vernier method.

Authors:  N Kirkham; D W Cotton
Journal:  J Clin Pathol       Date:  1984-02       Impact factor: 3.411

6.  The accuracy of clinical nodal staging and of limited axillary dissection as a determinant of histologic nodal status in carcinoma of the breast.

Authors:  B Fisher; N Wolmark; M Bauer; C Redmond; M Gebhardt
Journal:  Surg Gynecol Obstet       Date:  1981-06

Review 7.  Principles and guidelines for surgeons--management of symptomatic breast cancer. European Society of Surgical Oncology.

Authors:  M Blichert-Toft; M G Smola; L Cataliotti; N O'Higgins
Journal:  Eur J Surg Oncol       Date:  1997-04       Impact factor: 4.424

8.  A mathematical model of axillary lymph node involvement based on 1446 complete axillary dissections in patients with breast carcinoma.

Authors:  C I Kiricuta; J Tausch
Journal:  Cancer       Date:  1992-05-15       Impact factor: 6.860

9.  Probability of false negative nodal staging in conjunction with partial axillary dissection in breast cancer.

Authors:  J Kjaergaard; M Blichert-Toft; J A Andersen; F Rank; B V Pedersen
Journal:  Br J Surg       Date:  1985-05       Impact factor: 6.939

  9 in total
  6 in total

1.  The reliability of sampling three to six nodes for staging breast cancer.

Authors:  G Cserni
Journal:  J Clin Pathol       Date:  1999-09       Impact factor: 3.411

Review 2.  Axillary staging of breast cancer and the sentinel node.

Authors:  G Cserni
Journal:  J Clin Pathol       Date:  2000-10       Impact factor: 3.411

3.  The influence of nodal size on the staging of colorectal carcinomas.

Authors:  G Cserni
Journal:  J Clin Pathol       Date:  2002-05       Impact factor: 3.411

Review 4.  Sentinel lymph node assessment in breast cancer-an update on current recommendations.

Authors:  Gábor Cserni; Aoife Maguire; Simonetta Bianchi; Ales Ryska; Anikó Kovács
Journal:  Virchows Arch       Date:  2021-06-23       Impact factor: 4.064

5.  The axillary nodal harvest in breast cancer surgery is unchanged by sentinel node biopsy or the timing of surgery.

Authors:  B E Byrne; R I Cutress; J Gill; M H Wise; C Yiangou; A Agrawal
Journal:  Int J Breast Cancer       Date:  2012-05-30

6.  Occult axillary lymph node metastases are of no prognostic significance in breast cancer.

Authors:  R R Millis; R Springall; A H S Lee; K Ryder; E R C Rytina; I S Fentiman
Journal:  Br J Cancer       Date:  2002-02-01       Impact factor: 7.640

  6 in total

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