| Literature DB >> 10192967 |
L Z Lin1, S F Hu, M Chu, T M Chan, H Chai, C K Angerhofer, J M Pezzuto, G A Cordell.
Abstract
From the roots of Thalictrum faberi, six new phenolic aporphine-benzylisoquinoline alkaloids, 3-hydroxy-6'-desmethyl-9-O-methylthalifaboramine (1), 3-hydroxythalifaboramine (2), 6'-desmethylthalifaboramine (3); 3,5'-dihydroxythalifaboramine (4), 5'-hydroxythalifaboramine (5) and 3-hydroxy-6'-desmethylthalifaboramine (6) were isolated. Their structures were established through the use of one- and two-dimensional NMR techniques. All of the tested alkaloids showed potent cytotoxic and antimalarial activities.Entities:
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Year: 1999 PMID： 10192967 DOI： 10.1016/s0031-9422(98)00580-9
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072