Literature DB >> 10192418

Perphenazine distribution in a postmortem case.

B Levine1, A Jenkins, D Chute, J E Smialek.   

Abstract

The case of a 34-year-old, mentally challenged, Caucasian female found dead in a group home is presented. Empty containers of perphenazine and valproic acid were found next to her bed. The perphenazine had been prescribed to another patient. No anatomic cause of death was determined at autopsy. Comprehensive testing of the heart blood for ethanol and drugs identified perphenazine at a concentration of 4.4 mg/L and valproic acid at a concentration of 950 mg/L. The distribution of perphenazine in other specimens was consistent with previously reported phenothiazine cases. The medical examiner ruled that the cause of death in this case was multiple drug intoxication and the manner of death was suicide.

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Year:  1999        PMID: 10192418     DOI: 10.1093/jat/23.2.127

Source DB:  PubMed          Journal:  J Anal Toxicol        ISSN: 0146-4760            Impact factor:   3.367


  2 in total

1.  Identification of the human cytochrome P450 isoforms mediating in vitro N-dealkylation of perphenazine.

Authors:  O V Olesen; K Linnet
Journal:  Br J Clin Pharmacol       Date:  2000-12       Impact factor: 4.335

2.  Prolonged Drug-Drug Interaction between Terbinafine and Perphenazine.

Authors:  Young-Min Park
Journal:  Psychiatry Investig       Date:  2012-11-12       Impact factor: 2.505

  2 in total

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