| Literature DB >> 10191939 |
H Y Aboul-Enein1, C Doneanu, A Covaci.
Abstract
A simple capillary GC-MS method for the determination of melatonin from tablets is proposed. Melatonin (N-acetyl-5-methoxytryptamine) was determined by gas chromatography-mass spectrometry after extraction from ground tablets with ethyl acetate and derivatization with N-methyl-N-trimethylsilyl-heptafluorobutyramide (MTSHFBA). Splitless injection offers good reproducibility with a standard deviation of +/- 2%. The proposed method was applied to analyse the melatonin content from three different tablet formulations.Entities:
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Year: 1999 PMID： 10191939 DOI： 10.1002/(SICI)1099-0801(199902)13:1<24::AID-BMC765>3.0.CO;2-I
Source DB: PubMed Journal: Biomed Chromatogr ISSN： 0269-3879 Impact factor: 1.902