Literature DB >> 10191550

Human African trypanosomiasis: a latex agglutination field test for quantifying IgM in cerebrospinal fluid.

V Lejon1, P Büscher, N H Sema, E Magnus, N Van Meirvenne.   

Abstract

LATEX/IgM, a rapid agglutination test for the semi-quantitative detection of IgM in cerebrospinal fluid of patients with African trypanosomiasis, is described in this article. The lyophilized reagent has been designed for field use and remains stable at 45 degrees C for one year. The test has been evaluated on cerebrospinal fluid samples from trypanosome-infected and non-infected patients, by comparison with commercial latex agglutination, radial immunodiffusion, and nephelometry. All test systems yielded similar results.

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Year:  1998        PMID： 10191550      PMCID： PMC2312495     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  6 in total

1.  Immunoglobulin M in cerebrospinal fluid: reference values derived from 111 healthy individuals 18-88 years of age.

Authors:  K Blennow; I Skoog; A Wallin; C Wikkelsö; P Fredman
Journal:  Eur Neurol       Date:  1996       Impact factor: 1.710

2.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

3.  Cerebrospinal-fluid IgM in patients with sleeping-sickness.

Authors:  B M Greenwood; H C Whittle
Journal:  Lancet       Date:  1973-09-08       Impact factor: 79.321

4.  IgM and antibody measurement in the diagnosis and management of Gambian trypanosomiasis.

Authors:  H C Whittle; B M Greenwood; D E Bidwell; A Bartlett; A Voller
Journal:  Am J Trop Med Hyg       Date:  1977-11       Impact factor: 2.345

5.  Evaluation of immunoassays for diagnosis and management of sleeping sickness in Liberia.

Authors:  J Knobloch; F Tischendorf; J König; D Mehlitz
Journal:  Tropenmed Parasitol       Date:  1984-09

6.  Immune complexes in serum and in cerebrospinal fluid in African trypanosomiasis. Correlation with polyclonal B cell activation and with intracerebral immunoglobulin synthesis.

Authors:  P H Lambert; M Berney; G Kazyumba
Journal:  J Clin Invest       Date:  1981-01       Impact factor: 14.808
  6 in total
  5 in total

Review 1.  Options for field diagnosis of human african trypanosomiasis.

Authors:  François Chappuis; Louis Loutan; Pere Simarro; Veerle Lejon; Philippe Büscher
Journal:  Clin Microbiol Rev       Date:  2005-01       Impact factor: 26.132

2.  Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis.

Authors:  Enock Matovu; Anne Juliet Kazibwe; Claire Mack Mugasa; Joseph Mathu Ndungu; Zablon Kithingi Njiru
Journal:  J Trop Med       Date:  2012-03-27

3.  Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness.

Authors:  Natalia Tiberti; Alexandre Hainard; Veerle Lejon; Bertrand Courtioux; Enock Matovu; John Charles Enyaru; Xavier Robin; Natacha Turck; Krister Kristensson; Dieudonné Mumba Ngoyi; Gedeão M L Vatunga; Sanjeev Krishna; Philippe Büscher; Sylvie Bisser; Joseph Mathu Ndung'u; Jean-Charles Sanchez
Journal:  PLoS One       Date:  2012-07-18       Impact factor: 3.240

4.  Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense.

Authors:  Stijn Rogé; Liesbeth Van Nieuwenhove; Magali Meul; Annick Heykers; Annette Brouwer de Koning; Nicolas Bebronne; Yves Guisez; Philippe Büscher
Journal:  PLoS Negl Trop Dis       Date:  2014-07-17

5.  A multicentre, randomised, non-inferiority clinical trial comparing a nifurtimox-eflornithine combination to standard eflornithine monotherapy for late stage Trypanosoma brucei gambiense human African trypanosomiasis in Uganda.

Authors:  Freddie Kansiime; Seraphine Adibaku; Charles Wamboga; Franklin Idi; Charles Drago Kato; Lawrence Yamuah; Michel Vaillant; Deborah Kioy; Piero Olliaro; Enock Matovu
Journal:  Parasit Vectors       Date:  2018-02-22       Impact factor: 3.876
  5 in total

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