Literature DB >> 101877

Phencyclidine use among youth: history, epidemiology, and acute and chronic intoxication.

S E Lerner, R S Burns.   

Abstract

Phencyclidine use appears to be in a growth phase nationally. Factors contributing to the increasing popularity include the user's ability to control the dosage, an understanding of the immediate effects, and its availability. Those most at risk appear to be young Caucasian males. Phencyclidine-related problems are often like tips of icebergs, the underlying causes of which are hidden from public view. The problems often surface in the form of speech difficulties, memory loss, thinking disorders, personality changes, paranoia, severe depression, violence, accidents, suicides and homicides. Of particular concern to law enforcement personnel is the upsurge in phencyclidine-related violent crimes and carrying of weapons by users to protect themselves from their imagined persecutors. The evidence currently available supports the assumption that if there is a solution to the problem of phencyclidine abuse, that solution is prevention. Therefore, medical personnel and others within the helping professions must be alerted to the fact that phencyclidine is not just another drug problem. The findings from users we have already studied strongly suggest that phencyclidine is not an "upper" or a "downer," but perhaps an "insideouter", with longer term implications.

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Year:  1978        PMID: 101877

Source DB:  PubMed          Journal:  NIDA Res Monogr        ISSN: 1046-9516


  8 in total

1.  The social, behavioral, and health effects of phencyclidine (PCP) use.

Authors:  J G Sharp; D B Graeven
Journal:  J Youth Adolesc       Date:  1981-12

2.  Behavioural and electoencephalographic interactions between haloperidol and PCP/sigma ligands in the rat.

Authors:  S Sagratella; A Scotti de Carolis; A Pèzzola; P Popoli
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

3.  Phencyclidine: effects of chronic administration in the female mouse on gestation, maternal behavior, and the neonates.

Authors:  P J Goodwin; V J Perez; J C Eatwell; J L Palet; M T Jaworski
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

4.  Phencyclidine increases the affinity of dihydropyridine calcium channel antagonist binding in rat brain.

Authors:  G T Bolger; M F Rafferty; P Skolnick
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-09       Impact factor: 3.000

5.  Effects of phencyclidine on active avoidance and escape in rats.

Authors:  P Martin; M Manning; C Norman
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

6.  Agenesis of the vermis with fusion of the cerebellar hemispheres, septo-optic dysplasia and associated anomalies. Report of a case.

Authors:  J Michaud; E M Mizrahi; H Urich
Journal:  Acta Neuropathol       Date:  1982       Impact factor: 17.088

7.  Behavioral effects of chronic phencyclidine administration in rats.

Authors:  R D Sturgeon; R G Fessler; S F London; H Y Meltzer
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

8.  Epidemic of illicit drug use, mechanisms of action/addiction and stroke as a health hazard.

Authors:  Katherine Esse; Marco Fossati-Bellani; Angela Traylor; Sheryl Martin-Schild
Journal:  Brain Behav       Date:  2011-09       Impact factor: 2.708

  8 in total

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