Literature DB >> 1018177

Inhibition of vaccinia virus growth by the nucleoside analogue 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ribavirin).

E Katz, E Margalith, B Winer.   

Abstract

Virazole or Ribavirin (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) inhibits the growth of vaccinia virus at a concentration ode to a certain extent in the presence of Virazole, the DNA fails to acquire resistance to deoxyribonuclease and virus particles are not formed. Reversibility of the antiviral effect occurs when the drug is washed out from the infected cultures or when guanosine at an equimolar concentration is added.

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Year:  1976        PMID: 1018177     DOI: 10.1099/0022-1317-32-2-327

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  11 in total

1.  Replicon system for Lassa virus.

Authors:  Meike Hass; Uta Gölnitz; Stefanie Müller; Beate Becker-Ziaja; Stephan Günther
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

Review 2.  Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Authors:  E De Clercq
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

Review 3.  Ribavirin: a clinical overview.

Authors:  H Fernandez; G Banks; R Smith
Journal:  Eur J Epidemiol       Date:  1986-03       Impact factor: 8.082

4.  Vaccinia virus replication. I. Requirement for the host-cell nucleus.

Authors:  D E Hruby; L A Guarino; J R Kates
Journal:  J Virol       Date:  1979-02       Impact factor: 5.103

5.  Effects of ribavirin on the development of the Friend leukemia.

Authors:  U Opitz; H J Seidel; G Streissle
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

Review 6.  Ribavirin and inosiplex: a review of their present status in viral diseases.

Authors:  T W Chang; R C Heel
Journal:  Drugs       Date:  1981-08       Impact factor: 9.546

7.  Inhibition of lymphocyte proliferative responses by ribavirin.

Authors:  D L Peavy; W C Koff; D S Hyman; V Knight
Journal:  Infect Immun       Date:  1980-08       Impact factor: 3.441

8.  Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin.

Authors:  J J Kirsi; P A McKernan; N J Burns; J A North; B K Murray; R K Robins
Journal:  Antimicrob Agents Chemother       Date:  1984-10       Impact factor: 5.191

Review 9.  Direct-acting Antivirals and Host-targeting Agents against the Hepatitis A Virus.

Authors:  Tatsuo Kanda; Shingo Nakamoto; Shuang Wu; Masato Nakamura; Xia Jiang; Yuki Haga; Reina Sasaki; Osamu Yokosuka
Journal:  J Clin Transl Hepatol       Date:  2015-09-15

Review 10.  Antiviral Activity of Metal-Containing Polymers-Organotin and Cisplatin-Like Polymers.

Authors:  Michael R Roner; Charles E Carraher; Kimberly Shahi; Girish Barot
Journal:  Materials (Basel)       Date:  2011-05-27       Impact factor: 3.623

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