Literature DB >> 10179

Similarities between sodium channels in excitable membranes and in epithelia.

A W Cuthbert.   

Abstract

The inhibitory effects of the pyrazine derivative, amiloride, on sodium transport in an amphibian epithelium has been studied as a function of pH. It is concluded that the charged (guanidinium) group interacts with a negatively charged acid grouping in the membrane. Similarities between sodium channels in excitable membranes and epithelia are highlighted.

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Year:  1976        PMID： 10179     DOI： 10.1007/BF01953117

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  The influence of pH on equilibrium effects of tetrodotoxin on myelinated nerve fibres of Rana esculenta.

Authors:  W Ulbricht; H H Wagner
Journal:  J Physiol       Date:  1975-10       Impact factor: 5.182

2.  Charges and potentials at the nerve surface. Divalent ions and pH.

Authors:  B Hille
Journal:  J Gen Physiol       Date:  1968-02       Impact factor: 4.086

3.  Effects of tetrodotoxin on the mammalian kidney.

Authors:  T N Pullman; A R Lavender; I Aho
Journal:  Proc Natl Acad Sci U S A       Date:  1968-07       Impact factor: 11.205

4.  Potency difference between the zwitterion form and the cation forms of tetrodotoxin.

Authors:  G Camougis; B H Takman; J R Tasse
Journal:  Science       Date:  1967-06-23       Impact factor: 47.728

5.  The binding of labelled saxitoxin to the sodium channels in nerve membranes.

Authors:  R Henderson; J M Ritchie; G R Strichartz
Journal:  J Physiol       Date:  1973-12       Impact factor: 5.182

6.  Pharmacological modifications of the sodium channels of frog nerve.

Authors:  B Hille
Journal:  J Gen Physiol       Date:  1968-02       Impact factor: 4.086

7.  Ionic blockage of sodium channels in nerve.

Authors:  A M Woodhull
Journal:  J Gen Physiol       Date:  1973-06       Impact factor: 4.086

8.  Charge movement associated with the opening and closing of the activation gates of the Na channels.

Authors:  C M Armstrong; F Bezanilla
Journal:  J Gen Physiol       Date:  1974-05       Impact factor: 4.086

9.  The permeability of the sodium channel to organic cations in myelinated nerve.

Authors:  B Hille
Journal:  J Gen Physiol       Date:  1971-12       Impact factor: 4.086

10.  Direct measurement of uptake of sodium at the outer surface of the frog skin.

Authors:  T U Biber; P F Curran
Journal:  J Gen Physiol       Date:  1970-07       Impact factor: 4.086
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  2 in total

1.  Interdependence of the two borders in a sodium transporting epithelium. Possible regulation by the transport pool.

Authors:  A W Cuthbert; W K Shum
Journal:  J Membr Biol       Date:  1978       Impact factor: 1.843

2.  Irreversible inhibition of epithelial sodium channels by ultraviolet irradiation.

Authors:  A W Cuthbert; D D Fanestil; F C Herrera; S J Pryn
Journal:  Br J Pharmacol       Date:  1982-11       Impact factor: 8.739
  2 in total

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