CPK isoenzymes in evaluation of myocardial ischemic injury.

Enzymatic criteria for diagnosis of myocardial infarction have suffered from a lack of specificity, since enzyme elevations also occur in noncardiac disorders. The MB isoenzyme of creatine phosphokinase has provided a way out of this difficulty. Not only is it specific to injured myocardium but a recently developed plasma assay makes possible both diagnosis and, in many cases, measurement of the extent of damage.