OBJECTIVE: To investigate the cost-effectiveness of long-term therapy for Staphylococcus aureus bacteremia and to determine if an infectious diseases consultation affected the duration of therapy. METHODS: A decision analysis was performed based on data from the literature. To determine if consultation was related to therapy duration, a retrospective cohort study was performed using tightly matched pairs. RESULTS: The excess cost per life saved by long-term antibiotics was $500,000. The excess cost per life-year saved was $18,000. Nine pairs were matched. Patients who received consultation were more likely to receive long-term therapy than controls (median 41 days vs 15 days for controls, P = .04). CONCLUSIONS: The estimated cost per life-year saved by long-term therapy was similar to other accepted medical interventions. Infectious diseases consultation can encourage prolonged duration of antibiotic therapy for S aureus bacteremia.
OBJECTIVE: To investigate the cost-effectiveness of long-term therapy for Staphylococcus aureus bacteremia and to determine if an infectious diseases consultation affected the duration of therapy. METHODS: A decision analysis was performed based on data from the literature. To determine if consultation was related to therapy duration, a retrospective cohort study was performed using tightly matched pairs. RESULTS: The excess cost per life saved by long-term antibiotics was $500,000. The excess cost per life-year saved was $18,000. Nine pairs were matched. Patients who received consultation were more likely to receive long-term therapy than controls (median 41 days vs 15 days for controls, P = .04). CONCLUSIONS: The estimated cost per life-year saved by long-term therapy was similar to other accepted medical interventions. Infectious diseases consultation can encourage prolonged duration of antibiotic therapy for S aureus bacteremia.
Authors: J O Robinson; S Pozzi-Langhi; M Phillips; J C Pearson; K J Christiansen; G W Coombs; R J Murray Journal: Eur J Clin Microbiol Infect Dis Date: 2012-03-03 Impact factor: 3.267
Authors: Maud B P A Ariaans; Elisabeth A Roovers; Mark A A Claassen; Robert-Jan Hassing; Caroline M A Swanink; Elisabeth H Gisolf Journal: Eur J Clin Microbiol Infect Dis Date: 2018-04-18 Impact factor: 3.267
Authors: R B Saunderson; T Gouliouris; E K Nickerson; E J P Cartwright; A Kidney; S H Aliyu; N M Brown; D Limmathurotsakul; S J Peacock; M E Török Journal: Clin Microbiol Infect Date: 2015-05-29 Impact factor: 8.067
Authors: Rebecca B Saunderson; Theodore Gouliouris; Edward J Cartwright; Emma J Nickerson; Sani H Aliyu; D Roddy O'Donnell; Wilf Kelsall; D Limmathurotsakul; Sharon J Peacock; M Estée Török Journal: BMJ Open Date: 2014-07-01 Impact factor: 2.692
Authors: Julie Paulsen; Erik Solligård; Jan Kristian Damås; Andrew DeWan; Bjørn Olav Åsvold; Michael B Bracken Journal: Open Forum Infect Dis Date: 2016-03-01 Impact factor: 3.835