Biogenic amines in the Caenorhabditis briggsae.

Dopamine, epinephrine, norepinephrine and serotonin were demonstrated from homogenates of Caenrohabditis briggsae by two-dimensional thin layer chromotography and the identification confirmed by gas liquid chromtography. In Vitro studies with 14C precursors of these biogenic amines demonstrate the ability of C. briggsae to synthesize each compound. The results provide required preliminary data for studying the neurophysiology of aging utilizing the nematode as a model.