Literature DB >> 1016963

Induction of renal pelvic tumours in Sprague-Dawley rats by di-isopropanolnitrosamine.

G Reznik, U Mohr.   

Abstract

Transitional cell papillomas and carcinomas of the renal pelvis were observed in Sprague-Dawley rats after subcutaneous (s.c.) treatment with di-isopropranolnitrosamine (DIPN). These tumours occurred unilaterally and appeared as early as 24 weeks after the commencement of treatment. The tumours frequently filled the entire renal pelvis and compressed the kidney parenchyma. The malignant neoplasms demonstrated infiltrative growth into the adjacent medullary parenchyma.

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Year:  1976        PMID： 1016963     DOI： 10.1016/s0304-3835(76)80016-x

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  4 in total

1.  The carcinogenic effect of 2,2-dioxopropylnitrosamine on the renal pelvic epithelium of Sprague-Dawley rats, after chronic subcutaneous injections.

Authors:  M Solé; A Cardesa; J Domingo; U Mohr
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  Comparison of the effect of beta-oxidized dipropylnitrosamine metabolites administered at equimolar doses to Syrian hamsters.

Authors:  J Althoff; C Grandjean; P Pour; B Bertram
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1977-11-18

3.  Experimental models of kidney tumors.

Authors:  E Nogueira; A Cardesa; U Mohr
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

4.  Effect of di-isopropanolnitrosamine in European hamsters.

Authors:  G Reznik; U Mohr
Journal:  Br J Cancer       Date:  1977-10       Impact factor: 7.640
  4 in total

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