Literature DB >> 1016952

Proliferation of endocrine (APUD-type) cells during early N-diethylnitrosamine-induced lung carcinogenesis in hamsters.

H Reznik-Schüller.   

Abstract

Pronounced proliferation of amine precursor uptake and decarboxylase activity (APUD-type) cells was found in the segmental bronchi and bronchioles of Syrian golden hamsters during N-diethylnitrosamine (DEN)-induced lung carcinogenesis. Since similar epithelial alterations did not occur in previous experiments after benzo(a)pyrene (B(a)P) treatment, it is concluded that the initial stages of lung carcinogenesis differ with respect to the carcinogen administered.

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Year:  1976        PMID： 1016952     DOI： 10.1016/s0304-3835(75)97439-x

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  9 in total

1.  Quantitative study of pulmonary endocrine cells in anencephaly.

Authors:  T Ito; Y Nakatani; N Nagahara; T Ogawa; T Shibagaki; M Kanisawa
Journal:  Lung       Date:  1987       Impact factor: 2.584

2.  Ultrastructure of nitrosoheptamethyleneimine-induced lung tumors in European hamsters.

Authors:  H Reznik-Schüller
Journal:  Am J Pathol       Date:  1978-10       Impact factor: 4.307

Review 3.  Sequential morphologic alterations in the bronchial epithelium of Syrian golden hamsters during N-nitrosomorpholine-induced pulmonary tumorigenesis.

Authors:  H Reznik-Schüller
Journal:  Am J Pathol       Date:  1977-10       Impact factor: 4.307

4.  Endocrine cell proliferation in the rat lung following asbestos inhalation.

Authors:  N F Johnson; J C Wagner; H A Wills
Journal:  Lung       Date:  1980       Impact factor: 2.584

5.  Distribution and ultrastructural characteristics of Feyrter cells in the rat and hamster airway epithelium.

Authors:  N A Edmondson; D J Lewis
Journal:  Thorax       Date:  1980-05       Impact factor: 9.139

6.  Lung endocrine-like cells in hamsters treated with diethylnitrosamine: alterations in vivo and in cell culture.

Authors:  R I Linnoila; P Nettesheim; R P DiAugustine
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

7.  Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers.

Authors:  S M Aguayo; M A Kane; T E King; M I Schwarz; L Grauer; Y E Miller
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

8.  Responses of the lung to toxic injury.

Authors:  H Witschi
Journal:  Environ Health Perspect       Date:  1990-04       Impact factor: 9.031

Review 9.  Neuroendocrinelike (small granule) epithelial cells of the lung.

Authors:  R P DiAugustine; K S Sonstegard
Journal:  Environ Health Perspect       Date:  1984-04       Impact factor: 9.031
  9 in total

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