Literature DB >> 10160485

The impact of three influenza epidemics on primary care in England and Wales.

D M Fleming1.   

Abstract

The numbers of persons with influenza presenting to general practitioners in England and Wales during the epidemics of late 1989, late 1993, and early 1995 are estimated to be approximately 760,00, 480,000 and 192,000, respectively. The expected numbers used to derive these estimates were obtained by averaging incidence by week over the 9 winters of 1986/87 to 1994/95, excluding those weeks in which influenza was prevalent. These 3 epidemics varied in magnitude and in the relative impact on persons in different age groups. The influenza B epidemic in 1995 scarcely affected elderly people. During the 3 epidemic periods, increased numbers of persons consulted their general practitioners with other respiratory diseases, including pneumonia, acute bronchitis and otitis media. The patterns of increase were not consistent between the epidemics, partly because of the differing impact on the various age groups and partly because of the effect of other respiratory viral illnesses prevalent at the same time. No increase occurred in the numbers of persons reported with new episodes of cerebrovascular accident or of acute myocardial infarction. A similar method was used to estimate excess deaths, which amounted to 25,000 in 1989, 13,000 in 1993, and 500 in 1995. In the periods immediately following the influenza epidemics, the observed pattern of deaths conformed to the expected, demonstrating that persons dying during the epidemics were not just dying a few weeks prematurely.

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Year:  1996        PMID: 10160485     DOI: 10.2165/00019053-199600093-00010

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  14 in total

1.  Annual and seasonal variation in the incidence of common diseases.

Authors:  D M Fleming; C A Norbury; D L Crombie
Journal:  Occas Pap R Coll Gen Pract       Date:  1991-10

2.  Observations on the influenza epidemic of November/December 1989.

Authors:  D M Fleming; D L Crombie; C A Norbury; K W Cross
Journal:  Br J Gen Pract       Date:  1990-12       Impact factor: 5.386

3.  A new influenza surveillance system in France: the Ile-de-France "GROG". 1. Principles and methodology.

Authors:  C Hannoun; W Dab; J M Cohen
Journal:  Eur J Epidemiol       Date:  1989-09       Impact factor: 8.082

4.  Excess mortality from epidemic influenza, 1957-1966.

Authors:  J Housworth; A D Langmuir
Journal:  Am J Epidemiol       Date:  1974-07       Impact factor: 4.897

5.  Concurrence of monthly variations of mortality related to underlying cause in Europe.

Authors:  D L Crombie; D M Fleming; K W Cross; R J Lancashire
Journal:  J Epidemiol Community Health       Date:  1995-08       Impact factor: 3.710

6.  Influenza. The Birmingham Research Unit of the Royal College of General Practitioners.

Authors: 
Journal:  J R Coll Gen Pract       Date:  1977-09

7.  Respiratory illness and mortality in England and Wales. A study of the relationships between weekly data for the incidence of respiratory disease presenting to general practitioners, and registered deaths.

Authors:  D M Fleming; K W Cross; D L Crombie; R J Lancashire
Journal:  Eur J Epidemiol       Date:  1993-11       Impact factor: 8.082

Review 8.  The measurement of morbidity in general practice.

Authors:  D M Fleming
Journal:  J Epidemiol Community Health       Date:  1991-09       Impact factor: 3.710

9.  Incidence of episodes of acute asthma and acute bronchitis in general practice 1976-87.

Authors:  J G Ayres; N D Noah; D M Fleming
Journal:  Br J Gen Pract       Date:  1993-09       Impact factor: 5.386

10.  Respiratory syncytial virus or influenza?

Authors:  D M Fleming; K W Cross
Journal:  Lancet       Date:  1993 Dec 18-25       Impact factor: 79.321

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  9 in total

1.  The duration and magnitude of influenza epidemics: a study of surveillance data from sentinel general practices in England, Wales and the Netherlands.

Authors:  D M Fleming; M Zambon; A I Bartelds; J C de Jong
Journal:  Eur J Epidemiol       Date:  1999-05       Impact factor: 8.082

2.  Zanamivir for influenza: a public health perspective. Its use will require careful management by GPs.

Authors:  J S Nguyen-Van-Tam
Journal:  BMJ       Date:  1999-09-11

3.  Survey on influenza laboratory diagnostic and surveillance methods in Europe. European Scientific Working Group on Influenza.

Authors:  C Hannoun; B Tumova
Journal:  Eur J Epidemiol       Date:  2000-03       Impact factor: 8.082

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5.  A pharmacoeconomic model for the treatment of influenza.

Authors:  J A Mauskopf; S C Cates; A D Griffin
Journal:  Pharmacoeconomics       Date:  1999       Impact factor: 4.981

6.  Multiplex reverse transcription-PCR for surveillance of influenza A and B viruses in England and Wales in 1995 and 1996.

Authors:  J S Ellis; D M Fleming; M C Zambon
Journal:  J Clin Microbiol       Date:  1997-08       Impact factor: 5.948

7.  A reverse genetics approach for recovery of recombinant influenza B viruses entirely from cDNA.

Authors:  David Jackson; Andrew Cadman; Thomas Zurcher; Wendy S Barclay
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

8.  The role and response of primary healthcare services in the delivery of palliative care in epidemics and pandemics: A rapid review to inform practice and service delivery during the COVID-19 pandemic.

Authors:  Sarah Mitchell; Victoria Maynard; Victoria Lyons; Nicholas Jones; Clare Gardiner
Journal:  Palliat Med       Date:  2020-07-31       Impact factor: 4.762

9.  The common cold: a review of the literature.

Authors:  Dennis Wat
Journal:  Eur J Intern Med       Date:  2004-04       Impact factor: 4.487

  9 in total

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