Literature DB >> 10146996

Economic costs of functional dyspepsia.

O Nyrén1, G Lindberg, E Lindström, R Seensalu.   

Abstract

Dyspepsia is defined as chronic or recurrent symptoms believed to originate in the upper gastrointestinal tract. When routine investigation results in no identifiable explanation for those symptoms patients are labelled as having functional dyspepsia. In community-based surveys, approximately 30% of the otherwise apparently healthy population report dyspeptic symptoms and the majority are believed to have functional dyspepsia. Although only 1 in 4 or 5 patients make use of healthcare resources, this patient category is one of the largest in ambulatory care (1.6 to 5% of all consultations in general practice). The annual frequency of consultations for functional dyspepsia in Sweden has been estimated at 47 per 1000 population. In consequence of its high prevalence and associated absenteeism, the total costs of functional dyspepsia are considerable. In Sweden in 1981, the costs were estimated at $US55 000 per 1000 population ($US113 630 in 1991 dollars). The most cost-effective management strategy remains to be defined. Evidence is accumulating that the traditional 'wait-and-see' policy with initial empirical therapeutic trials without investigation may not be the most cost conserving strategy.

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Year:  1992        PMID: 10146996     DOI: 10.2165/00019053-199201050-00003

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  84 in total

Review 1.  Definition and investigation of dyspepsia. Consensus of an international ad hoc working party.

Authors:  L Barbara; M Camilleri; R Corinaldesi; G P Crean; R C Heading; A G Johnson; J R Malagelada; V Stanghellini; M Wienbeck
Journal:  Dig Dis Sci       Date:  1989-08       Impact factor: 3.199

2.  Anamnestic and psychological features in diagnosis and prognosis of functional abdominal complaints: a prospective study.

Authors:  G Bleijenberg; J F Fennis
Journal:  Gut       Date:  1989-08       Impact factor: 23.059

3.  A formal approach to symptoms in dyspepsia.

Authors:  R P Knill-Jones
Journal:  Clin Gastroenterol       Date:  1985-07

4.  Evidence for hypomotility in non-ulcer dyspepsia: a prospective multifactorial study.

Authors:  B Waldron; P T Cullen; R Kumar; D Smith; J Jankowski; D Hopwood; D Sutton; N Kennedy; F C Campbell
Journal:  Gut       Date:  1991-03       Impact factor: 23.059

Review 5.  The efficacy of endoscopy in the evaluation of dyspepsia. A review of the literature and development of a sound strategy.

Authors:  K L Kahn; S Greenfield
Journal:  J Clin Gastroenterol       Date:  1986-06       Impact factor: 3.062

6.  The "epigastric distress syndrome". A possible disease entity identified by history and endoscopy in patients with nonulcer dyspepsia.

Authors:  O Nyrén; H O Adami; S Gustavsson; P G Lindgren; L Lööf; A Nyberg
Journal:  J Clin Gastroenterol       Date:  1987-06       Impact factor: 3.062

7.  Diagnosis and treatment of dyspepsia. A cost-effectiveness analysis.

Authors:  L Read; T M Pass; A L Komaroff
Journal:  Med Decis Making       Date:  1982       Impact factor: 2.583

8.  Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin.

Authors:  R Gotthard; G Bodemar; U Brodin; K A Jönsson
Journal:  Scand J Gastroenterol       Date:  1988-01       Impact factor: 2.423

Review 9.  Definitions of dyspepsia.

Authors:  R C Heading
Journal:  Scand J Gastroenterol Suppl       Date:  1991

10.  General practice and teaching hospital use of barium meal examinations in the City and Hackney Health District.

Authors:  B G Conry; A M McLean; M J Farthing
Journal:  Postgrad Med J       Date:  1986-04       Impact factor: 2.401

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  20 in total

Review 1.  Natural history of dyspepsia.

Authors:  Lars Agréus
Journal:  Gut       Date:  2002-05       Impact factor: 23.059

2.  Cost-effective prescribing in elderly people.

Authors:  D J Morgan; C A Sutters; B Livesley
Journal:  Pharmacoeconomics       Date:  1992-06       Impact factor: 4.981

3.  Problems with implementing guidelines: a randomised controlled trial of consensus management of dyspepsia.

Authors:  R H Jones; S Lydeard; J Dunleavey
Journal:  Qual Health Care       Date:  1993-12

4.  Is health care seeking for irritable bowel syndrome and functional dyspepsia a socially learned response to illness?

Authors:  Natasha A Koloski; Philip M Boyce; Nicholas J Talley
Journal:  Dig Dis Sci       Date:  2005-01       Impact factor: 3.199

5.  Natural course of functional dyspepsia after Helicobacter pylori eradication: a seven-year survey.

Authors:  Francesco di Mario; Nicoletta Stefani; Nadia Dal Bò; Massimo Rugge; Alberto Pilotto; Giulia Martina Cavestro; Lucas Giovanni Cavallaro; Angelo Franzé; Gioacchino Leandro
Journal:  Dig Dis Sci       Date:  2005-12       Impact factor: 3.199

6.  General practitioners' views on the over-the-counter availability of H2-antagonists.

Authors:  J Erwin; N Britten; R Jones
Journal:  Br J Gen Pract       Date:  1997-02       Impact factor: 5.386

7.  Treatment of functional dyspepsia.

Authors:  Smita L S Halder; Nicholas J Talley
Journal:  Curr Treat Options Gastroenterol       Date:  2005-08

8.  Functional Dyspepsia: A New Rome III Paradigm.

Authors:  Smita L S Halder; Nicholas J Talley
Journal:  Curr Treat Options Gastroenterol       Date:  2007-08

Review 9.  Current management strategies and emerging treatments for functional dyspepsia.

Authors:  Michael Camilleri; Vincenzo Stanghellini
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-02-05       Impact factor: 46.802

10.  Guidelines on appropriate indications for upper gastrointestinal endoscopy. Working Party of the Joint Committee of the Royal College of Physicians of London, Royal College of Surgeons of England, Royal College of Anaesthetists, Association of Surgeons, the British Society of Gastroenterology, and the Thoracic Society of Great Britain.

Authors:  A T Axon; G D Bell; R H Jones; M A Quine; R F McCloy
Journal:  BMJ       Date:  1995-04-01
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