Literature DB >> 10146944

The cost of asthma: can it be reduced?

C M Mellis1, J K Peat, A J Woolcock.   

Abstract

Asthma is a major public health problem in developed countries, where it consumes a large and increasing share of scarce health resources. Ideally, medical management should be both optimal in terms of improving the patient's quality of life, and cost-effective for society. At present, there is very little information relating to costs and economic efficiency of current asthma management. Although the true total cost of asthma is unknown, current estimates suggest it is high. The main value of recent total cost estimates is that they identify the most expensive areas of asthma costs, and ideally, formal cost-effectiveness analyses should be concentrated on these areas. Asthma is still under- or inappropriately diagnosed, and undertreated. Several national and international consensus plans for the optimal management of asthma in children and adults have been published. If these inadequacies in asthma management were corrected, using current treatment recommendations, the overall cost of asthma from both the community and patient perspective should fall. The situation requires increased use of preventative medications {sodium cromoglycate (cromolyn sodium) or inhaled corticosteroids}, more widespread use of written crisis plans, more proactive medical consultations (rather than reactive or urgent consultations), further expansion of asthma education programmes, and further education of medical practitioners about the optimum management of both long term asthma and the acute exacerbation of asthma in the patient's home, the doctor's office, the hospital emergency room and the hospital inpatient setting. The increased costs associated with these measures would be more than offset by reduced expenditure on bronchodilator drugs, less widespread use of nebulisers at home and in hospitals, reduced antibiotic usage, reduced need for expensive emergency medical care and particularly reduced utilisation of hospital resources. To ensure that resources are being directed into the most cost-effective areas of asthma care, clinical trials of asthma should include utilisation of healthcare resources as an outcome measure, and estimates of the costs of the treatment under study. In addition, since the intangible cost (quality of life) is one of the most important effects of treatment from the patient's perspective, this should be more widely used as an outcome measure in clinical trials. Ultimately, prevention of asthma is the long term goal. If the hypothesis that sensitisation to house dust mite in early infancy is a major contributor to the subsequent development of asthma, then prevention may require drastic and expensive changes to current housing.

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Year:  1993        PMID: 10146944     DOI: 10.2165/00019053-199303030-00004

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  90 in total

1.  An economic evaluation of asthma in the United States.

Authors:  K B Weiss; P J Gergen; T A Hodgson
Journal:  N Engl J Med       Date:  1992-03-26       Impact factor: 91.245

2.  Facilitated referral to asthma specialist reduces relapses in asthma emergency room visits.

Authors:  R S Zeiger; S Heller; M H Mellon; J Wald; R Falkoff; M Schatz
Journal:  J Allergy Clin Immunol       Date:  1991-06       Impact factor: 10.793

3.  Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma.

Authors:  C Burke; C K Power; A Norris; A Condez; B Schmekel; L W Poulter
Journal:  Eur Respir J       Date:  1992-01       Impact factor: 16.671

4.  Increased incidence of asthma in children of smoking mothers.

Authors:  F D Martinez; M Cline; B Burrows
Journal:  Pediatrics       Date:  1992-01       Impact factor: 7.124

5.  The assessment and treatment of asthma: a conference report.

Authors:  F E Hargreave; J Dolovich; M T Newhouse
Journal:  J Allergy Clin Immunol       Date:  1990-06       Impact factor: 10.793

6.  Methylprednisolone therapy for acute asthma in infants and toddlers: a controlled clinical trial.

Authors:  A Tal; N Levy; J E Bearman
Journal:  Pediatrics       Date:  1990-09       Impact factor: 7.124

7.  Comparison of bronchial reactivity and peak expiratory flow variability measurements for epidemiologic studies.

Authors:  B G Higgins; J R Britton; S Chinn; S Cooper; P G Burney; A E Tattersfield
Journal:  Am Rev Respir Dis       Date:  1992-03

8.  Lifestyle changes in mild asthma during intermittent symptom-related use of terbutaline inhaled via 'Turbohaler'.

Authors:  M Northfield; R K Patel; A Richardson; M D Taylor; P D Richardson
Journal:  Curr Med Res Opin       Date:  1991       Impact factor: 2.580

9.  Underdiagnosis and undertreatment of asthma in childhood.

Authors:  A N Speight; D A Lee; E N Hey
Journal:  Br Med J (Clin Res Ed)       Date:  1983-04-16

10.  The cost and effectiveness of an education program for adults who have asthma.

Authors:  M B Bolton; B C Tilley; J Kuder; T Reeves; L R Schultz
Journal:  J Gen Intern Med       Date:  1991 Sep-Oct       Impact factor: 5.128

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  11 in total

Review 1.  Cost-of-illness studies. Useful for health policy?

Authors:  M A Koopmanschap
Journal:  Pharmacoeconomics       Date:  1998-08       Impact factor: 4.981

Review 2.  The economic costs of asthma: a review and conceptual model.

Authors:  K B Weiss; S D Sullivan
Journal:  Pharmacoeconomics       Date:  1993-07       Impact factor: 4.981

Review 3.  The economic aspects of drug delivery in asthma.

Authors:  R J Massie; C M Mellis
Journal:  Pharmacoeconomics       Date:  1997-05       Impact factor: 4.981

4.  Acute respiratory admissions in Thessaloniki, Greece: 14-year follow-up.

Authors:  E Hatziagorou; F Kirvassilis; S Saraphidou; M Katsara; R Valeri; M Emporiadou; C Magnisali; J Tsanakas
Journal:  Hippokratia       Date:  2009-10       Impact factor: 0.471

5.  Cost effectiveness of budesonide/formoterol for maintenance and reliever therapy versus salmeterol/fluticasone plus salbutamol in the treatment of asthma.

Authors:  Gunnar Johansson; Emma B Andreasson; Per E Larsson; Claus F Vogelmeier
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

6.  Characterisation of asthma management in the Fallon Community Health Plan from 1988 to 1991.

Authors:  S F Lanes; B M Birmann; A M Walker; A L Sheffer; R A Rosiello; B E Lewis; N A Dreyer
Journal:  Pharmacoeconomics       Date:  1996-10       Impact factor: 4.981

7.  Concurrent oral and inhalation drug delivery using a dual formulation system: the use of oral theophylline carrier with combined inhalable budesonide and terbutaline.

Authors:  Rania O Salama; Paul M Young; Daniela Traini
Journal:  Drug Deliv Transl Res       Date:  2014-06       Impact factor: 4.617

Review 8.  Salmeterol. An appraisal of its quality-of-life benefits and potential pharmacoeconomic positioning in asthma.

Authors:  D H Peters; D Faulds
Journal:  Pharmacoeconomics       Date:  1995-06       Impact factor: 4.981

9.  Cost effectiveness of fluticasone and budesonide in patients with moderate asthma.

Authors:  K O Steinmetz; T Volmer; M Trautmann; A Kielhorn
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

Review 10.  Glucocorticosteroid treatment of asthma.

Authors:  T R Bai
Journal:  Can Fam Physician       Date:  1995-11       Impact factor: 3.275

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