Literature DB >> 101300

Primary management of operable breast cancer by minimal surgery and radiotherapy.

S Alpert, N A Ghossein, P Stacey, F A Migliorelli, G Efron, V Krishnaswamy.   

Abstract

109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgically resectable cancers (T1, T2, T3, N0, N1) had a minimum followup of two years (average 4 years +/- 3 months). Absolute and determinate survivals NED were 65% and 86%. There were four local recurrences (8%). Secondary mastectomy could be performed on three. Microscopic involvement of the surgical margin by cancer did not alter the local control rate. The cosmetic results were good in 98%. Gross removal of the tumor followed by radiotherapy may be offered as an alternative to mastectomy in patients with operable breast cancer.

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Year:  1978        PMID: 101300     DOI: 10.1002/1097-0142(197810)42:4<2054::aid-cncr2820420456>3.0.co;2-7

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  5 in total

1.  Partial mastectomy for breast cancer.

Authors:  N A Ghossein
Journal:  Br Med J       Date:  1979-02-10

2.  The surgeon's role in breast cancer: changing concepts.

Authors:  H P Leis
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

3.  Treatment of primary breast cancer without mastectomy. The Los Angeles community experience and review of the literature.

Authors: 
Journal:  Ann Surg       Date:  1986-08       Impact factor: 12.969

4.  Lumpectomy and irradiation in the treatment of early carcinoma of the breast.

Authors:  R R Deffebach; R L Goodman; L Miller
Journal:  West J Med       Date:  1982-04

5.  Irradiation as an alternative to mastectomy for early breast cancer.

Authors:  A Martinez; D Clarke
Journal:  West J Med       Date:  1983-05
  5 in total

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