Analysis of a temperature sensitive mutation in gene cII of bacteriophage lambda.

The mutation cIIts612 was found to map outside the immunity region of phage lambdaimm21 hybrid. As expected of a cII mutation, lambdacIIts612 is unable to stimulate either cI repressor or Int synthesis during the establishment of lysogeny. These results indicate that part of the cII gene of lambda is homologous to that of lambdaimm21 phage.