Literature DB >> 101224

Anaesthesia for studies of the cerebral circulation: a comparison of phencyclidine and althesin in the baboon.

W Fitch, A P McGeorge, E T MacKenzie.   

Abstract

The effects of phencyclidine on cerebral blood flow, cerebral metabolic rate for oxygen and carbon dioxide reactivity were compared with those of Althesin in six baboons. Under similar and stable levels (Stage 1) of electroencephalographic activity cerebral blood flow and the cerebral metabolic rate for oxygen were significantly less during the infusion of Althesin when compared with the values obtained during the infusion of phencyclidine. Reactivity to carbon dioxide was present and similar during the infusion of either drug.

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Year:  1978        PMID： 101224     DOI： 10.1093/bja/50.10.985

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  3 in total

1.  Delayed effects of subarachnoid haemorrhage on cerebral metabolism and the cerebrovascular response to hypercapnia in the primate.

Authors:  D P Boisvert; J D Pickard; D I Graham; W Fitch
Journal:  J Neurol Neurosurg Psychiatry       Date:  1979-10       Impact factor: 10.154

2.  Effects of hypotension induced with sodium nitroprusside on the cerebral circulation before, and one week after, the subarachnoid injection of blood.

Authors:  W Fitch; J D Pickard; A Tamura; D I Graham
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-01       Impact factor: 10.154

3.  The effect of sodium salicylate on cerebral blood flow and metabolism.

Authors:  J D Pickard; J E Rose; M D Shaw; A Strathdee
Journal:  Br J Pharmacol       Date:  1980-03       Impact factor: 8.739
  3 in total

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