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Literature DB >> 1011019

Neuromyotonia: an unusual presentation of intrathoracic malignancy.

Abstract

A 48 year old woman is described who presented with increasing muscular rigidity and who was found to have a mediastinal tumour. Electrophysiological studies revealed that the muscular stiffness resulted from very high frequency motor unit activity which outlasted voluntary effort, and which was abolished by nerve block. The abnormal activity may have arisen at the anterior horn cell level. Marked improvement followed the administration of diphenylhydantoin.

Entities: Chemical Disease Species

Mesh：

Substances：
Phenytoin
Glycogen

Year: 1976 PMID： 1011019 PMCID： PMC1083308 DOI： 10.1136/jnnp.39.11.1086

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

12 in total

1. A new and effective drug in the treatment of the stiff-man syndrome: preliminary report.

Authors: F M HOWARD
Journal: Proc Staff Meet Mayo Clin Date: 1963-05-22

2. Intense rigidity of the arms due to isolation of motoneurones by a spinal tumour.

Authors: G RUSHWORTH; W A LISHMAN; J T HUGHES; D R OPPENHEIMER
Journal: J Neurol Neurosurg Psychiatry Date: 1961-05 Impact factor: 10.154

3. The "stiff-man" syndrome. A report of two further cases.

Authors: W H TRETHOWAN; J L ALLSOP; B TURNER
Journal: Arch Neurol Date: 1960-10

4. Progressive fluctuating muscular rigidity and spasm ("stiff-man" syndrome); report of a case and some observations in 13 other cases.

Authors: F P MOERSCH; H W WOLTMAN
Journal: Proc Staff Meet Mayo Clin Date: 1956-07-25

5. Mitochondrial myopathy with multisystem abnormalities and normal ocular movements.

Authors: J G McLeod; W de C Baker; C D Shorey; C B Kerr
Journal: J Neurol Sci Date: 1975-01 Impact factor: 3.181

6. The neuropathy of multiple myeloma. An electrophysiological and histological study.

Authors: J C Walsh
Journal: Arch Neurol Date: 1971-11

7. Alcoholic neuropathy. An electrophysiological and histological study.

Authors: J C Walsh; J G McLeod
Journal: J Neurol Sci Date: 1970-05 Impact factor: 3.181

8. Generalized muscular stiffness, fasciculations, and myokymia of peripheral nerve origin.

Authors: W E Wallis; A Van Poznak; F Plum
Journal: Arch Neurol Date: 1970-05

9. Syndrome of continuous muscle fibre activity. Histochemical, nerve terminal and end-plate study of two cases.

Authors: H Isaacs; G Frere
Journal: S Afr Med J Date: 1974-08-10

10. Neurogenic muscular atrophy of infancy with prolonged survival. The variable course of Werdnig-Hoffmann Disease.

Authors: T L Munsat; R Woods; W Fowler; C M Pearson
Journal: Brain Date: 1969-03 Impact factor: 13.501

9 in total

1. Morvan's fibrillary chorea: a paraneoplastic manifestation of thymoma.

Authors: E K Lee; R A Maselli; W G Ellis; M A Agius
Journal: J Neurol Neurosurg Psychiatry Date: 1998-12 Impact factor: 10.154

2. Concurrence of myasthenia gravis and chorée fibrillaire de Morvan.

Authors: Y Iwasaki; M Kinoshita; K Ikeda; K Takamiya; T Shiojima
Journal: Eur Arch Psychiatry Neurol Sci Date: 1990

3. Neuromuscular, autonomic and central cholinergic hyperactivity associated with thymoma and acetylcholine receptor-binding antibody.

Authors: M Halbach; V Hömberg; H J Freund
Journal: J Neurol Date: 1987-08 Impact factor: 4.849

Review 4. Stiff muscles.

Authors: P D Thompson
Journal: J Neurol Neurosurg Psychiatry Date: 1993-02 Impact factor: 10.154