Literature DB >> 1010772

Accidental laboratory infection with Treponema pallidum, Nichols strain.

J J Fitzgerald, R C Johnson, M Smith.   

Abstract

This case report describes a laboratory-acquired infection with Treponema pallidum, Nichols strain. The specific details of the accidental exposure are presented, along with a description of the clinical observations. This infection indicates that the rabbit adapted Nichols strain of T pallidum retains its capability to infect humans. In addition, aerosols of concentrated preparations of these organisms, generated within the laboratory, represent a definite biohazard.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 1010772

Source DB:  PubMed          Journal:  J Am Vener Dis Assoc        ISSN： 0095-148X


  9 in total

1.  Antibody responses elicited against the Treponema pallidum repeat proteins differ during infection with different isolates of Treponema pallidum subsp. pallidum.

Authors:  Brandon T Leader; Karin Hevner; Barbara J Molini; Lynn K Barrett; Wesley C Van Voorhis; Sheila A Lukehart
Journal:  Infect Immun       Date:  2003-10       Impact factor: 3.441

2.  Characterization and serologic analysis of the Treponema pallidum proteome.

Authors:  Melanie A McGill; Diane G Edmondson; James A Carroll; Richard G Cook; Ralph S Orkiszewski; Steven J Norris
Journal:  Infect Immun       Date:  2010-04-12       Impact factor: 3.441

3.  In vitro culture system to determine MICs and MBCs of antimicrobial agents against Treponema pallidum subsp. pallidum (Nichols strain).

Authors:  S J Norris; D G Edmondson
Journal:  Antimicrob Agents Chemother       Date:  1988-01       Impact factor: 5.191

4.  Infections acquired in clinical laboratories in Utah.

Authors:  J T Jacobson; R B Orlob; J L Clayton
Journal:  J Clin Microbiol       Date:  1985-04       Impact factor: 5.948

Review 5.  Genetic diversity in Treponema pallidum: implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws.

Authors:  David Smajs; Steven J Norris; George M Weinstock
Journal:  Infect Genet Evol       Date:  2011-12-15       Impact factor: 3.342

6.  Molecular cloning and characterization of a 35.5-kilodalton lipoprotein of Treponema pallidum.

Authors:  C L Hubbard; F C Gherardini; P J Bassford; L V Stamm
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

7.  TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain.

Authors:  Rebecca E LaFond; Arturo Centurion-Lara; Charmie Godornes; Wesley C Van Voorhis; Sheila A Lukehart
Journal:  Infect Immun       Date:  2006-03       Impact factor: 3.441

8.  Genetics of Treponema: relationship between Treponema pallidum and five cultivable treponemes.

Authors:  R Miao; A H Fieldsteel
Journal:  J Bacteriol       Date:  1978-01       Impact factor: 3.490

9.  In Vitro Cultivation of the Syphilis Spirochete Treponema pallidum.

Authors:  Diane G Edmondson; Steven J Norris
Journal:  Curr Protoc       Date:  2021-02
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.